ArticleIndian journal of nephrology
IgA Nephropathy with Wilson's Disease: A Case Report and Literature Review.
Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Case Report: A case of focal segmental glomerulosclerosis in Wilson's disease induced by penicillamine.Frontiers in medicine · 2026Article
- Article
- Kidney involvement in Wilson's disease: a review of the literature.Clinical kidney journal · 2024Review
- A child with abdominal pain, arthralgia, palpable skin rash, hepatosplenomegaly, and pancytopenia: Answers.Pediatric nephrology (Berlin, Germany) · 2023Article
- Secondary IgA Nephropathy and IgA-Associated Nephropathy: A Systematic Review of Case Reports.Journal of clinical medicine · 2023Review
- Clinical features and familial mutations in the coexistence of Wilson's disease and Alport syndrome: A case report.Frontiers in pediatrics · 2023Article
- Identification of key cuproptosis-related genes and their targets in patients with IgAN.BMC nephrology · 2022Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most common glomerulonephritis seen in the world is immunoglobulin A nephropathy (IgAN). It can be primary or secondary associated with various conditions like Chronic Liver disease, Crohn's disease, neoplasms, etc. However, IgAN secondary to Wilson's disease is very rare. A 9 year old boy presented with gross hematuria and proteinuria. He had a history of recurrent jaundice in the past. Ultrasonography (USG) whole abdomen showed altered echotexture of the liver with normal-sized kidneys. An extended workup for liver disease was done, and the diagnosis of Wilson's disease was confirmed with decreased serum ceruloplasmin levels, increased urinary copper, and the Kayser-Fleischer ring. Urine routine microscopy showed numerous red blood cells, few red blood cell casts, and mild proteinuria. Renal biopsy showed IgAN. The patient was started on D-penicillamine. On follow-up at 3 months, he showed complete resolution of proteinuria and hematuria. Thus, we suggest that Wilson's disease should be considered as one of the causes of secondary IgAN in pediatric patients with hematuria, proteinuria with liver dysfunction.
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