ArticleScientific reports2021
A population-based study of TyG index distribution and its relationship to cardiometabolic risk factors in children and adolescents.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effect of exercise intervention on the triglyceride-glucose (TyG) index in adolescents with overweight or obesity: a systematic review and Bayesian dose-response meta-analysis.BMC pediatrics · 2025Pooled it
- Nine anthropometric insulin resistance indices predict mortality and life expectancy across glucose states.iScience · 2026Article
- Article
- Analysis of the prevalence of dyslipidemia in early-onset schizophrenia patients and its correlation with clinical characteristics.Frontiers in psychiatry · 2026Article
- Palmitic acid intake in children on gluten-free and generalized diets before and after palm oil reformulation: nutritional and metabolic implications.Frontiers in nutrition · 2026Article
- Blood Pressure Levels and Triglyceride-Glucose Index: A Cross-Sectional Study from a Nationwide Screening in Mongolia.Journal of clinical medicine · 2025Article
- The Association Between the Triglyceride-Glucose Index and the Risk of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study.Life (Basel, Switzerland) · 2025Article
- Elevated Triglyceride-Glucose Index Is Associated With Insulin Resistance, Metabolic Syndrome Components, Nonalcoholic Fatty Liver Disease, and Adverse Pregnancy Outcomes in Chinese Women With Polycystic Ovary Syndrome.Clinical endocrinology · 2025Article
- Triglyceride-glucose index: a novel assessment tool for all-cause mortality in critical stroke patients-a retrospective analysis of the eICU-CRD database.Cardiovascular diabetology · 2025Observational
- Association between the combination of the triglyceride-glucose index and obesity-related indices with hyperuricemia among children and adolescents in China.Lipids in health and disease · 2025Article
- The Role of Gender in the Relationship Between Waist-to-Hip Ratio, Triglyceride-Glucose Index, and Insulin Resistance in Korean Children.Healthcare (Basel, Switzerland) · 2025Article
- Association of triglyceride-glucose index with bone mineral density and fracture: a systematic review.Diabetology & metabolic syndrome · 2025Review
- Triglyceride-glucose index as a marker in cardiovascular diseases; a bibliometric study and visual analysis.Annals of medicine and surgery (2012) · 2025Review
- Relationship of the Degree of Sarcopenia with the Severity of Nonalcoholic Fatty Liver Disease and Cardiometabolic Risk in Adolescents.Life (Basel, Switzerland) · 2024Article
- Association between triglyceride-glucose index and all-cause mortality in critically ill patients with ischemic stroke: analysis of the MIMIC-IV database.Cardiovascular diabetology · 2023Article
- Comparison of the ability of HOMA-IR, VAI, and TyG indexes to predict metabolic syndrome in children with obesity: a cross-sectional study.BMC pediatrics · 2023Article
- Association of novel lipid indicators with the risk of stroke among participants in Central China: a population-based prospective study.Frontiers in endocrinology · 2023Article
- Predictive effect of triglyceride-glucose index on clinical events in patients with acute ischemic stroke and type 2 diabetes mellitus.Cardiovascular diabetology · 2022Article
- Metabolic Syndrome and Cardiometabolic Risk Factors in the Mixed Hypercholesterolemic Populations with Respect to Gender, Age, and Obesity in Asir, Saudi Arabia.International journal of environmental research and public health · 2022Article
- Association of the triglyceride-glucose index with weight-adjusted appendicular lean mass in Chinese adolescents aged 12-18 years old.Scientific reports · 2022Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to present age- and sex-specific distributions of the triglyceride-glucose (TyG) index and to evaluate their relationship with cardiometabolic risk factors in children and adolescents. A total of 7404 participants aged 10-18 years from the Korean National Health and Nutrition Survey were included as the reference population. The TyG index was calculated as ln(fasting triglyceride [mg/dL] × fasting glucose [mg/dL]/2). The percentile of the TyG index exhibited a steady linear relationship with age for both sexes. TyG index significantly correlated with waist circumference (WC) standard deviation score (SDS; r = 0.110, p < 0.001), systolic blood pressure (SBP; r = 0.104, p < 0.001), diastolic blood pressure (DBP; r = 0.083, p < 0.001), glucose (r = 0.220, p < 0.001), high-density lipoprotein cholesterol (HDL-C; r = - 0.325, p < 0.001), and triglycerides (TG; r = 0.926, p < 0.001). Multiple linear regression analysis revealed that the TyG index was significantly associated with WC SDS (β = 0.116, p < 0.001), SBP (β = 2.009, p < 0.001), DBP (β = 1.464, p < 0.001), glucose (β = 3.376, p < 0.001), HDL-C (β = - 6.431, p < 0.001), and TG (β = 85.518, p < 0.001). Our results suggest that the TyG index has a steady linear distribution for sex and age in children and adolescents and constitutes an indicator for predicting metabolic disorders that could lead to cardiovascular disease later in life.
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