ArticleScientific reports2021
Effect of reward on electrophysiological signatures of grid cell population activity in human spatial navigation.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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2 authors at 1 institution in 1 country.
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Abstract
The regular equilateral triangular periodic firing pattern of grid cells in the entorhinal cortex is considered a regular metric for the spatial world, and the grid-like representation correlates with hexadirectional modulation of theta (4-8 Hz) power in the entorhinal cortex relative to the moving direction. However, researchers have not clearly determined whether grid cells provide only simple spatial measures in human behavior-related navigation strategies or include other factors such as goal rewards to encode information in multiple patterns. By analysing the hexadirectional modulation of EEG signals in the theta band in the entorhinal cortex of patients with epilepsy performing spatial target navigation tasks, we found that this modulation presents a grid pattern that carries target-related reward information. This grid-like representation is influenced by explicit goals and is related to the local characteristics of the environment. This study provides evidence that human grid cell population activity is influenced by reward information at the level of neural oscillations.
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