Evidence map›Paper›PMID 34880301›Full record

ArticleScientific reports2021

Robust, fiducial-free drift correction for super-resolution imaging.

Michael J Wester, David J Schodt, Hanieh Mazloom-Farsibaf, Mohamadreza Fazel, Sandeep Pallikkuth, Keith A Lidke

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
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  7. Review
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  9. A Versatile Drift-Free Super-Resolution Imaging Method via Oblique Bright-Field Correlation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael J WesterDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, NM, 87131, USA.
David J SchodtDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, NM, 87131, USA.
Hanieh Mazloom-FarsibafDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, NM, 87131, USA.
Mohamadreza FazelDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, NM, 87131, USA.
Sandeep PallikkuthDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, NM, 87131, USA.
Keith A LidkeDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, NM, 87131, USA. klidke@unm.edu.

Funding

UNM TRAININGP50GM085273 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LIDKE, KEITH A · 2009 to 2018
$26.1M
Measuring Protein-Protein Interactions using SPT-RESOLFTR21GM132716 · NIGMS · UNIVERSITY OF NEW MEXICO · PI LIDKE, KEITH A · 2019 to 2020
$393k
Multi-target super-resolution imaging using sequential labelingR21EB019589 · NIBIB · UNIVERSITY OF NEW MEXICO · PI LIDKE, KEITH A · 2015 to 2016
$390k
NIBIB NIH HHS R21 EB019589NIGMS NIH HHS P50 GM085273NIGMS NIH HHS R21 GM132716
6 · The paper itself

Abstract

We describe a robust, fiducial-free method of drift correction for use in single molecule localization-based super-resolution methods. The method combines periodic 3D registration of the sample using brightfield images with a fast post-processing algorithm that corrects residual registration errors and drift between registration events. The method is robust to low numbers of collected localizations, requires no specialized hardware, and provides stability and drift correction for an indefinite time period.

Indexed as

AutomationAlgorithmsCell LineFluorescent Antibody TechniqueHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMicroscopySoftware

Identifiers

PMID34880301
PMCPMC8655078

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.