ArticleNature communications2021
Engineering Bacillus subtilis for the formation of a durable living biocomposite material.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Bioprinted core-shell living material platform for spatially controlled encapsulation ofBioactive materials · 2027Article
- De Novo Autogenic Engineered Living Functional Materials.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Molecular and Biosafety Perspectives of Bacterial Self-Healing Concrete: From Sporulation and Biomineralization to Public Health Implications.Materials (Basel, Switzerland) · 2026Review
- SynBio-DSP: an integrated synthetic biology platform with fed-batch fermentation and continuous downstream processing for sustainable production of thermostable cellulases.Biotechnology for biofuels and bioproducts · 2026Article
- Programmable Semi-Interpenetrating Living Materials With Robust Stability for Versatile Bioremediation and Biotherapeutics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Living Hydrogels: Harnessing Microorganism-Material Synergy for Next-Generation Therapeutics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- PEARL: Protein Eluting Alginate with Recombinant Lactobacilli.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Bacterially grown living materials with resistant and on-demand functionality.Science advances · 2025Article
- Article
- Bacterial Species in Engineered Living Materials: Strategies and Future Directions.Microbial biotechnology · 2025Review
- Strength in diversity: unlocking the full potential of engineered living materials with multistrain collaboration.FEMS microbiology reviews · 2025Review
- Mechanically Tunable, Compostable, Healable and Scalable Engineered Living Materials.Nature communications · 2024Article
- Transcriptional regulation of living materials via extracellular electron transfer.Nature chemical biology · 2024Article
- Positive effects of molybdenum on the biomineralization process on the surface of low-alloy steel catalyzed byFrontiers in microbiology · 2024Article
- Living Material with Temperature-Dependent Light Absorption.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Living microecological hydrogels for wound healing.Science advances · 2023Article
- Bioresource Upgrade for Sustainable Energy, Environment, and Biomedicine.Nano-micro letters · 2023Review
- A de novo matrix for macroscopic living materials from bacteria.Nature communications · 2022Article
- Engineered Living Hydrogels.Advanced materials (Deerfield Beach, Fla.) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Engineered living materials (ELMs) are a fast-growing area of research that combine approaches in synthetic biology and material science. Here, we engineer B. subtilis to become a living component of a silica material composed of self-assembling protein scaffolds for functionalization and cross-linking of cells. B. subtilis is engineered to display SpyTags on polar flagella for cell attachment to SpyCatcher modified secreted scaffolds. We engineer endospore limited B. subtilis cells to become a structural component of the material with spores for long-term storage of genetic programming. Silica biomineralization peptides are screened and scaffolds designed for silica polymerization to fabricate biocomposite materials with enhanced mechanical properties. We show that the resulting ELM can be regenerated from a piece of cell containing silica material and that new functions can be incorporated by co-cultivation of engineered B. subtilis strains. We believe that this work will serve as a framework for the future design of resilient ELMs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.