Evidence map›Paper›PMID 34879993›Full record

ReviewClinical lymphoma, myeloma & leukemia2022

SOHO State of the Art Updates and Next Questions: Treatment of Older, Vulnerable Adults with Multiple Myeloma.

Shakira J Grant, Girija Joshi, Brea Lipe

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical lymphoma, myeloma & leukemia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shakira J GrantDepartment of Medicine, Division of Hematology, The University of North Carolina at Chapel Hill, Chapel Hill, NC; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Girija JoshiDepartment of Medicine, Division of Hematology, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Brea LipeDepartment of Medicine, Division of Hematology-Oncology, University of Rochester, Rochester, NY. Electronic address: brea_lipe@urmc.rochester.edu.

Funding

UNC Oncology K12K12CA120780 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WILLIAM Y. KIM · 2007 to 2026
$9.6M
Functional Trajectories and Illness Experiences of Older Adults with Multiple MyelomaR03AG074030 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GRANT, SHAKIRA JEANENE · 2021 to 2022
$311k
NCI NIH HHS K12 CA120780NIA NIH HHS R03 AG074030
6 · The paper itself

Abstract

Multiple myeloma is primarily a disease of the elderly, and optimal treatments must weigh the risks of toxicity with the benefits of therapy.  Frailty scales have been developed to aid treatment-decision making for older adults with MM.   This review provides a framework for incorporating frailty scales into clinical care and highlights how patient-aligned priorities for care can influence the management of older or more vulnerable adults with newly diagnosed multiple myeloma newly diagnosed multiple myeloma. We review the currently available systemic therapies for managing older or more vulnerable adults with newly diagnosed multiple myeloma otherwise considered ineligible for autologous stem cell transplantation.

Indexed as

FrailtyHematopoietic Stem Cell TransplantationMultiple MyelomaAgedHumansTransplantation, Autologous

Identifiers

PMID34879993
PMCPMC9050878

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.