Evidence map›Paper›PMID 34879646›Full record

ArticleHaematologica2022

Early testicular maturation is sensitive to depletion of spermatogonial pool in sickle cell disease.

Klara M Benninghoven-Frey, Nina Neuhaus, Atte K Lahtinen, Claudia Krallmann, Joana M D Portela, Andrea Jarisch, Verena Nordhoff, Armin Soave, Hajar A M Ba Omar, Mikael Sundin and 4 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 4 countries.

Klara M Benninghoven-FreyCentre of Reproductive Medicine and Andrology, University of Münster and University Clinic Münster, Münster.
Nina NeuhausCentre of Reproductive Medicine and Andrology, University of Münster and University Clinic Münster, Münster.
Atte K LahtinenApplied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Department of Medical and Clinical Genetics / Medicum, Faculty of Medicine, University of Helsinki, Helsinki.
Claudia KrallmannCentre of Reproductive Medicine and Andrology, University of Münster and University Clinic Münster, Münster.
Joana M D PortelaCenter for Reproductive Medicine, Research Institute Reproduction and Development, Amsterdam Universitair Medische Centra, University of Amsterdam, Amsterdam.
Andrea JarischDivision of Stem Cell Transplantation and Immunology, Department of Children and Adolescent Medicine, University Hospital Frankfurt, Johann Wolfgang Goethe University, Frankfurt am Main.
Verena NordhoffCentre of Reproductive Medicine and Andrology, University of Münster and University Clinic Münster, Münster.
Armin SoaveDepartment of Urology, University Medical Center Hamburg-Eppendorf, Hamburg.
Hajar A M Ba OmarNORDFERTIL Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, Stockholm.
Mikael SundinDivision of Paediatrics, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden; Section of Hematology, Immunology and HCT, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm.
Cecilia LangenskiöldDepartment of Pediatric Oncology, The Queen Silvia Children's Hospital, Gothenburg.
Sabine KlieschCentre of Reproductive Medicine and Andrology, University of Münster and University Clinic Münster, Münster.
Jan-Bernd StukenborgNORDFERTIL Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, Stockholm.
Kirsi JahnukainenNORDFERTIL Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden; New Children's Hospital, Paediatric Research Centre, University of Helsinki and Helsinki University Hospital, Helsinki. Kirsi.Jahnukainen@ki.se.
University of Münster · DEKarolinska University Hospital · SEUniversity Hospital Münster · DEUniversity of Helsinki · FIAmsterdam University Medical Centers · NLDrottning Silvias barn- och ungdomssjukhus · SEKarolinska Institutet · SEUniversity Hospital Frankfurt · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anemia, Sickle CellSpermatogoniaHumansMale

Identifiers

PMID34879646
PMCPMC8972172
OpenAlexW4200165947

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.