Evidence map›Paper›PMID 34879491›Full record

ArticleThe American journal of emergency medicine2021

Clinical and operational impact of rapid point-of-care SARS-CoV-2 detection in an emergency department.

Camille Gerlier, Benoît Pilmis, Olivier Ganansia, Alban Le Monnier, Jean-Claude Nguyen Van

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04786249 (Impact of Rapid Screening for COVID-19 in Delocalized Biology in the Emergency Department), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04786249 completednot on this map

Impact of Rapid Screening for COVID-19 in Delocalized Biology in the Emergency Department

TypeobservationalSponsorFondation Hôpital Saint-JosephRan2021 to 2022Enrolled2,488ConditionsCovid19
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Point of Care Tests: Changing Paradigms in the Diagnosis of SARS-CoV-2.Heart views : the official journal of the Gulf Heart Association
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Camille GerlierService des Urgences, Groupe Hospitalier Paris Saint-Joseph, Paris, France.
Benoît PilmisEquipe Mobile de Microbiologie Clinique, Groupe Hospitalier Paris Saint-Joseph, Paris, France; Institut Micalis, UMR 1319, Université Paris-Saclay, INRAe, AgroParisTech, Bactéries Pathogènes et Santé, Châtenay-Malabry, France.
Olivier GanansiaService des Urgences, Groupe Hospitalier Paris Saint-Joseph, Paris, France.
Alban Le MonnierInstitut Micalis, UMR 1319, Université Paris-Saclay, INRAe, AgroParisTech, Bactéries Pathogènes et Santé, Châtenay-Malabry, France; Service de Microbiologie Clinique et Plateforme de Dosage des Anti-infectieux, Groupe Hospitalier, Paris, France.
Jean-Claude Nguyen VanService de Microbiologie Clinique et Plateforme de Dosage des Anti-infectieux, Groupe Hospitalier, Paris, France. Electronic address: jcnguyen@ghpsj.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectiveRapid point-of-care (POC) SARS-CoV-2 detection with Abbott ID NOW™ COVID-19 test has been implemented in our Emergency Department (ED) for several months. We aimed to evaluate the operational impact and potential benefits of this innovative clinical pathway.

methodsWe conducted a prospective, descriptive, interventional, non-randomized study, before-after trial with the comparison of patient cohorts from two consecutive periods of seven weeks (observational pre-POC period vs interventional POC period).

resultsIn 2020, throughout weeks 37 to 50, 3333 patients were assessed for eligibility and among them 331 (9.9%) were positive for SARS-CoV-2 infections. Among the included patients, 136 (9.2%) were positive for SARS-CoV-2 infection in the pre-POC period and 195 (10.5%) in the POC period. Among positive patients for SARS-CoV-2 related infection in-hospital mortality rate was similar between the two groups but the hospitalization rate was higher in the POC group (81.6% vs. 65.4%; p < 0.001). More patients in the POC period were able to leave the ED within 6 h. We examined rates of antibiotic, anticoagulant, and corticosteroid prescriptions among patients tested for SARS-CoV-2 in the ED. Only the rate of prescribed anticoagulants was found to be higher in the POC period (40% vs. 24.2%; p < 0.003).

conclusionWe demonstrated that COVID-19 point-of-care testing speeds up clinical decision-making, improving use of recommended treatments for COVID-19, such as anticoagulants. Moreover, it improves the boarding time and significantly shortened the length of stay in the ED for patients requiring outpatient care.

Indexed as

COVID-19 TestingEmergency Service, HospitalPoint-of-Care TestingAgedAged, 80 and overCohort StudiesControlled Before-After StudiesCOVID-19FemaleHospitalizationHumansMaleMiddle AgedSARS-CoV-2Cilnical impactEmergency departmentIDNOW COVID-19Isothermal nucleic acid amplification technologyNAATNicking enzyme amplification reaction technologyOperational impactPoint-of-careSARS-CoV-2

Identifiers

PMID34879491
PMCPMC8479552

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.