Evidence map›Paper›PMID 34879241›Full record

ArticleCell metabolism2021

Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2.

Moritz Reiterer, Mangala Rajan, Nicolás Gómez-Banoy, Jennifer D Lau, Luis G Gomez-Escobar, Lunkun Ma, Ankit Gilani, Sergio Alvarez-Mulett, Evan T Sholle, Vasuretha Chandar and 18 more

Open access · bronzeAbstract readPublished Erratum
In one paragraph

Article in Cell metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. The prognostic significance of insulin resistance in COVID-19: a review.Journal of diabetes and metabolic disorders · 2024
    Review
  12. Review
  13. SARS-CoV-2 Infection Alters the Phenotype and Gene Expression of Adipocytes.International journal of molecular sciences · 2024
    Article
  14. Review
  15. Article
  16. COVID-19, Obesity, and GRP78: Unraveling the Pathological Link.Journal of obesity & metabolic syndrome · 2023
    Review
  17. Article
  18. Acupoint stimulation for long COVID: A promising intervention:.World journal of acupuncture-moxibustion · 2023
    Review
  19. SARS-CoV-2 fires up inflammation in adipose tissue.Nature reviews. Endocrinology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors.

Moritz Reiterer
Mangala Rajan
Nicolás Gómez-Banoy
Jennifer D Lau
Luis G Gomez-Escobar
Lunkun Ma
Ankit Gilani
Sergio Alvarez-Mulett
Evan T Sholle
Vasuretha Chandar
Yaron Bram
Katherine Hoffman
Priya Bhardwaj
Phoebe Piloco
Alfonso Rubio-Navarro
Skyler Uhl
Lucia Carrau
Sean Houhgton
David Redmond
Alpana P Shukla
Parag Goyal
Kristy A Brown
Benjamin R tenOever
Laura C Alonso
Robert E Schwartz
Edward J Schenck
Monika M Safford
James C Lo

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Dusp26 regulation of beta cell homeostasisR01DK121140 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI James C Lo · 2020 to 2026
$2.7M
Optimization of the engineered 3D hepatic microenvironment enhances pluripotent stem cell derived hepatocyteR01DK121072 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI SCHWARTZ, ROBERT E · 2020 to 2024
$2.6M
Obesity Increases Breast Cancer Penetrance in BRCA Mutation Carriers: A Role for Local and Systemic FactorsR01CA215797 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI BROWN, KRISTY A. · 2017 to 2021
$2.6M
An Obesity-Induced Kinase that Regulates Adipose Homeostasis and Metabolic DiseasesR01DK121844 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI LO, JAMES C · 2019 to 2023
$2.1M
Modeling Hepatoblastoma using pluripotent stem cell derived hepatocyte-like cellsR01CA234614 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SCHWARTZ, ROBERT E · 2019 to 2023
$1.9M
NCATS NIH HHS UL1 TR002384NCI NIH HHS R01 CA215797NIDDK NIH HHS R01 DK121072NIDDK NIH HHS R01 DK121140NIDDK NIH HHS R01 DK121844
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID34879241
PMCPMC8650200
OpenAlexW4225908051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.