Evidence map›Paper›PMID 34879147›Full record

ReviewNutrition reviews2021

Bioactives in bovine milk: chemistry, technology, and applications.

Tiantian Lin, Gopinathan Meletharayil, Rohit Kapoor, Alireza Abbaspourrad

Open access · bronzeAbstract readReview
In one paragraph

Review in Nutrition reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

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  5. Genomic Insights and Inactivation Strategies forFoods (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tiantian LinDepartment of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York, USA.ORCID 0000-0002-1816-3380
Gopinathan MeletharayilGopinathan Meletharayil and Rohit Kapoor are with the National Dairy Council, Rosemont, Illinois, USA.
Rohit KapoorGopinathan Meletharayil and Rohit Kapoor are with the National Dairy Council, Rosemont, Illinois, USA.
Alireza AbbaspourradDepartment of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York, USA.ORCID 0000-0001-5617-9220
Cornell University · USDairy Management · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The significance of dairy in human health and nutrition is gaining significant momentum as consumers continue to desire wholesome, nutritious foods to fulfill their health and wellness needs. Bovine milk not only consists of all the essential nutrients required for growth and development, it also provides a broad range of bioactive components that play an important role in managing human homeostasis and immune function. In recent years, milk bioactives, including α-lactalbumin, lactoferrin, glycomacropeptide, milk fat globule membrane, and milk oligosaccharides, have been intensively studied because of their unique bioactivity and functionality. Challenges for the application of these bioactive components in food and pharmaceutical formulations are associated with their isolation and purification on an industrial scale and also with their physical and chemical instability during processing, storage, and digestion. These challenges can be overcome by advanced separation techniques and sophisticated nano- or micro-encapsulation technologies. Current knowledge about the chemistry, separation, and encapsulation technology of major bioactives derived from bovine milk and their application in the food industry is reviewed here.

Indexed as

LactalbuminMilkAnimalsHumansMilk, HumanMilk ProteinsNutritional StatusOligosaccharidesTechnologyLactalbuminMilk ProteinsOligosaccharidesbioactive componentsbovine milkencapsulationglycomacropeptidelactoferrinmilk fat globule membranemilk oligosaccharidesseparationα-lactalbumin

Identifiers

PMID34879147
PMCPMC8653947
OpenAlexW4200524748

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.