Evidence map›Paper›PMID 34878934›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2022

Developing portable widefield fundus camera for teleophthalmology: Technical challenges and potential solutions.

Xincheng Yao, Taeyoon Son, Jiechao Ma

Abstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Biophotonics discovery · 2025
    Article
  2. The Use Of Fundus Photography In The Emergency Room-A Review.Current neurology and neuroscience reports · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Multispectral Fundus Photography of Choroidal Nevi with Trans-Palpebral Illumination.medRxiv : the preprint server for health sciences · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xincheng YaoDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0002-0356-3242
Taeyoon SonDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0001-7273-5880
Jiechao MaDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.ORCID 0000-0002-7307-8402

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AAKALU, VINAY · 1985 to 2025
$14.8M
Functional imaging of retinal photoreceptorsR01EY023522 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 2014 to 2024
$3.5M
Nonmydriatic ultra-widefield fundus photography employing trans-pars-planar illuminationR01EY029673 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHAN, ROBISON VERNON PAUL, YAO, XINCHENG · 2019 to 2022
$1.8M
Differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathyR01EY030842 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LIM, JENNIFER IRENE, YAO, XINCHENG · 2020 to 2023
$1.7M
Functional tomography of neurovascular coupling interactions in healthy and diseased retinasR01EY030101 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 2019 to 2022
$1.4M
A portable ultra-widefield fundus camera for nonmydriatic examination of retinopathy of prematurityR44EY028786 · NEI · BIOLIGHT ENGINEERING, LLC · PI CHAN, ROBISON VERNON PAUL, SON, TAEYUN · 2020 to 2021
$1.2M
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY023522NEI NIH HHS R01 EY029673NEI NIH HHS R01 EY030101NEI NIH HHS R01 EY030842NEI NIH HHS R44 EY028786
6 · The paper itself

Abstract

A portable, low cost, widefield fundus camera is essential for developing affordable teleophthalmology. However, conventional trans-pupillary illumination used in traditional fundus cameras limits the field of view (FOV) in a snapshot image, and frequently requires pharmacologically pupillary dilation for reliable examination of eye conditions. This minireview summarizes recent developments in alternative illumination approaches for widefield fundus photography. Miniaturized indirect illumination has been used to enable compact design for developing low cost, portable, widefield fundus camera. Contact mode trans-pars-planar illumination has been validated for ultra-widefield fundus imaging of infant eyes. Contact-free trans-pars-planar illumination has been explored for widefield imaging of adult eyes. Trans-palpebral illumination has been also demonstrated in a smartphone-based widefield fundus imager to foster affordable teleophthalmology.

Indexed as

Eye DiseasesOphthalmologyTelemedicineDiagnostic Techniques, OphthalmologicalFundus OculiHumansPhotographychoroideyeFundus camerafundus photographyophthalmologyretina

Identifiers

PMID34878934
PMCPMC8899340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.