Evidence map›Paper›PMID 34878889›Full record

ArticleJournal of virology2022

Rab1b-GBF1-ARF1 Secretory Pathway Axis Is Required for Birnavirus Replication.

María C Gimenez, Yesica R Frontini-Lopez, Cristian A Pocognoni, Julieta S Roldán, Clara García Samartino, Marina Uhart, María I Colombo, Mauricio R Terebiznik, Laura R Delgui

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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  5. The Formation and Function ofInternational journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

María C GimenezIHEM, Universidad Nacional de Cuyo, CONICET, Mendoza, Argentina.
Yesica R Frontini-LopezIHEM, Universidad Nacional de Cuyo, CONICET, Mendoza, Argentina.
Cristian A PocognoniIHEM, Universidad Nacional de Cuyo, CONICET, Mendoza, Argentina.
Julieta S RoldánInstituto de Investigaciones Biotecnológicas "Dr. Rodolfo A. Ugalde" (IIBIO), Universidad Nacional de San Martín (UNSAM), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Martín, Buenos Aires, Argentina.
Clara García SamartinoFacultad de Ciencias Médicas, Universidad Nacional de Cuyo, Mendoza, Argentina.
Marina UhartIHEM, Universidad Nacional de Cuyo, CONICET, Mendoza, Argentina.
María I ColomboIHEM, Universidad Nacional de Cuyo, CONICET, Mendoza, Argentina.
Mauricio R TerebiznikDepartment of Biological Sciences and Department of Cell and System Biology, University of Torontogrid.17063.33 at Scarborough, Scarborough, Canada.ORCID 0000-0002-5111-2219
Laura R DelguiIHEM, Universidad Nacional de Cuyo, CONICET, Mendoza, Argentina.ORCID 0000-0002-3647-3593
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidad Nacional de Cuyo · ARUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Birnaviruses are members of the Birnaviridae family, responsible for major economic losses to poultry and aquaculture. The family is composed of nonenveloped viruses with a segmented double-stranded RNA (dsRNA) genome. Infectious bursal disease virus (IBDV), the prototypic family member, is the etiological agent of Gumboro disease, a highly contagious immunosuppressive disease in the poultry industry worldwide. We previously demonstrated that IBDV hijacks the endocytic pathway for establishing the viral replication complexes on endosomes associated with the

Indexed as

ADP-Ribosylation Factor 1AnimalsBrefeldin ACell LineEndosomesGolgi ApparatusGuanine Nucleotide Exchange FactorsHost-Pathogen InteractionsInfectious bursal disease virusPyridinesQuinolinesrab1 GTP-Binding ProteinsSecretory PathwayViral Replication CompartmentsVirus ReplicationADP-Ribosylation Factor 1Brefeldin Agolgicide AGuanine Nucleotide Exchange FactorsPyridinesQuinolinesrab1 GTP-Binding ProteinsArf1birnavirusendosomesGBF1Golgi complexRab1secretory pathway

Identifiers

PMID34878889
PMCPMC8865525
OpenAlexW4200018712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.