Evidence map›Paper›PMID 34878811›Full record

ArticleApplied and environmental microbiology2022

Transcriptome Analysis of Pseudomonas aeruginosa Biofilm Infection in an

Niamh E Harrington, Jenny L Littler, Freya Harrison

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Bridging bench and bedside: translational omics ofEuropean respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Article
  4. Review
  5. Microbiology (Reading, England) · 2026
    Article
  6. ThemBio · 2026
    Article
  7. BioMed research international · 2026
    Review
  8. Article
  9. Simulated Media for Mimicking the Human Environment In Vitro.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Recreating chronic respiratory infectionsEuropean respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  17. Article
  18. Role of Efflux Pumps on Antimicrobial Resistance inInternational journal of molecular sciences · 2022
    Review
  19. Review
  20. Transcriptional Profiling of Pseudomonas aeruginosa Infections.Advances in experimental medicine and biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Niamh E HarringtonSchool of Life Sciences, Gibbet Hill Campus, The University of Warwickgrid.7372.1, Coventry, United Kingdom.
Jenny L LittlerSchool of Life Sciences, Gibbet Hill Campus, The University of Warwickgrid.7372.1, Coventry, United Kingdom.
Freya HarrisonSchool of Life Sciences, Gibbet Hill Campus, The University of Warwickgrid.7372.1, Coventry, United Kingdom.ORCID 0000-0001-8449-5095
University of Warwick · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M01116X/1Medical Research Council MR/R001898/1
6 · The paper itself

Abstract

Pseudomonas aeruginosa is the predominant cause of chronic biofilm infections that form in the lungs of people with cystic fibrosis (CF). These infections are highly resistant to antibiotics and persist for years in the respiratory tract. One of the main research challenges is that current laboratory models do not accurately replicate key aspects of a P. aeruginosa biofilm infection, highlighted by previous RNA-sequencing studies. We compared the P. aeruginosa PA14 transcriptome in an

Indexed as

Cystic FibrosisPseudomonas InfectionsAnimalsAnti-Bacterial AgentsBiofilmsGene Expression ProfilingHumansLungPseudomonas aeruginosaQuality of LifeSwineAnti-Bacterial Agentsantibiotic resistanceantimicrobial resistancebiofilmbiofilmschronic infectioncystic fibrosisex vivo modelPseudomonas aeruginosaquorum sensingRNAseqRNA sequencingtranscriptome

Identifiers

PMID34878811
PMCPMC8824274
OpenAlexW4221077960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.