Evidence map›Paper›PMID 34878724›Full record

ArticleVeterinary medicine and science2022

Carboxymethyl chitosan bounded iron oxide nanoparticles and gamma-irradiated avian influenza subtype H9N2 vaccine to development of immunity on mouse and chicken.

Farahnaz Motamedi-Sedeh, Atefeh Saboorizadeh, Iraj Khalili, Massomeh Sharbatdaran, Viskam Wijewardana, Arash Arbabi

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 4 countries.

Farahnaz Motamedi-SedehDepartment of Veterinary and Animal Science, Nuclear Agriculture Research School, Nuclear Science and Technology Research Institute, Karaj, Iran.ORCID 0000-0003-3388-9670
Atefeh SaboorizadehDepartment of Microbiology, Science Faculty, Islamic Azad University, Karaj Branch, Karaj, Iran.
Iraj KhaliliRazi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization, Karaj, Iran.
Massomeh SharbatdaranPhysics and accelerator Research School, Nuclear Science and Technology Research Institute, Tehran, Iran.
Viskam WijewardanaDepartment of Nuclear Sciences and Applications, Animal Production and Health Section, International Atomic Energy Agency (IAEA), Vienna International Centre (VIC), Vienna, Austria.ORCID 0000-0002-5787-8792
Arash ArbabiFaulty of Medical Science, Tehran University of Medical Science, Tehran, Iran.
Animal Science Research Institute · CNAtomic Energy Organization of Iran · IRInternational Atomic Energy Agency · ATIslamic Azad University, Karaj · IRRazi Vaccine and Serum Research Institute · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAvian influenza virus (AIV) subtype H9N2 is a low pathogenic avian influenza virus (LPAIV).

objectiveThis study aims to evaluate the humoral and cellular immunity in vaccinated mice and broiler chicken by irradiated AIV antigen plus carboxymethyl chitosan bounded iron oxide nanoparticles (CMC-IO NPs) as an adjuvant.

methodsAIV subtype H9N2 with 10

resultsBased on the comparison between the two X-ray diffraction (XRD) patterns on Fe

conclusionsAccordingly, Th2 activation represented no increase. Finally, the finding showed that AIV-IO-CMC was effective on enhancing immunogenicity as irradiated AIV antigen administered with a clinically acceptable adjuvant (i.e. IO-CMC).

Indexed as

ChitosanInfluenza A Virus, H9N2 SubtypeInfluenza in BirdsInfluenza VaccinesAnimalsAntigens, ViralChickensFormaldehydeGamma RaysMagnetic Iron Oxide NanoparticlesMiceAntigens, ViralChitosanFormaldehydeInfluenza Vaccinesavian influenza viruscarboxymethyl chitosangamma irradiationiron oxidenanoparticles

Identifiers

PMID34878724
PMCPMC8959295
OpenAlexW4200269515

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.