Evidence map›Paper›PMID 34878679›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2022

Release of Molecular Cargo from Polymer Systems by Mechanochemistry.

Robin Küng, Robert Göstl, Bernd M Schmidt

Open access · hybridAbstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 71 citations in OpenAlex.

  1. Forces in mechanically interlocked materials.Chemical Society reviews · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Visible-Light Switchable Rings and Chains in Dynamic Covalent Imine Chemistry.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Semi-Telechelic Polymers from Mechanochemical C─C Bond Activation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  14. Article
  15. Furan Release via Force-Promoted Retro-[4+2][3+2] Cycloaddition.Journal of the American Chemical Society · 2023
    Article
  16. Article
  17. Off-center Mechanophore Activation in Block Copolymers.Angewandte Chemie (International ed. in English) · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Robin KüngInstitut für Organische Chemie und Makromolekulare Chemie, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany.
Robert GöstlDWI - Leibniz Institute for Interactive Materials, Forckenbeckstr. 50, 52056, Aachen, Germany.ORCID http://orcid.org/0000-0002-7483-6236
Bernd M SchmidtInstitut für Organische Chemie und Makromolekulare Chemie, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany.ORCID http://orcid.org/0000-0003-3622-8106
Heinrich Heine University Düsseldorf · DEDWI – Leibniz Institute for Interactive Materials · DE

Funding

Jürgen Manchot StiftungMinisterium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-WestfalenVolkswagen Foundation 92888
6 · The paper itself

Abstract

The design and manipulation of (multi)functional materials at the nanoscale holds the promise of fuelling tomorrow's major technological advances. In the realm of macromolecular nanosystems, the incorporation of force-responsive groups, so called mechanophores, has resulted in unprecedented access to responsive behaviours and enabled sophisticated functions of the resulting structures and advanced materials. Among the diverse force-activated motifs, the on-demand release or activation of compounds, such as catalysts, drugs, or monomers for self-healing, are sought-after since they enable triggering pristine small molecule function from macromolecular frameworks. Here, we highlight examples of molecular cargo release systems from polymer-based architectures in solution by means of sonochemical activation by ultrasound (ultrasound-induced mechanochemistry). Important design concepts of these advanced materials are discussed, as well as their syntheses and applications.

Indexed as

Mechanical PhenomenaPolymersCatalysisMacromolecular SubstancesUltrasonographyMacromolecular SubstancesPolymersdrug releasemechanochemistrypolymerssonochemistryultrasound

Identifiers

PMID34878679
PMCPMC9306765
OpenAlexW4200569193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.