Evidence map›Paper›PMID 34878315›Full record

ArticleJournal of feline medicine and surgery2022

Evaluation of gastrointestinal transit times and pH in healthy cats using a continuous pH monitoring system.

Naila J Telles, Bradley T Simon, Elizabeth M Scallan, Emily N Gould, Mark G Papich, Yuqing He, Mu-Tien Lee, Jonathan A Lidbury, Jörg M Steiner, Aarti Kathrani and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. In Vitro Acid Resistance of Feline-DerivedJournal of fungi (Basel, Switzerland) · 2026
    Article
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  5. Review
  6. Review
  7. Pharmacokinetics of Amoxicillin in the Cat.Journal of veterinary pharmacology and therapeutics · 2025
    Article
  8. Effects of aAnimals : an open access journal from MDPI · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Endoscopic administration of Coca-Cola for medical management of a wedged intestinal trichobezoar in a cat.The Canadian veterinary journal = La revue veterinaire canadienne · 2023
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Naila J TellesGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
Bradley T SimonDepartment of Small Animal Clinical Sciences, Texas A&M University, College Station, TX, USA.
Elizabeth M ScallanDepartment of Small Animal Clinical Sciences, Texas A&M University, College Station, TX, USA.
Emily N GouldGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
Mark G PapichNorth Carolina State University, Raleigh, NC, USA.
Yuqing HeNorth Carolina State University, Raleigh, NC, USA.
Mu-Tien LeeNorth Carolina State University, Raleigh, NC, USA.
Jonathan A LidburyGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
Jörg M SteinerGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
Aarti KathraniRoyal Veterinary College, London, UK.
M Katherine TolbertGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.ORCID 0000-0001-8725-9530
Texas A&M University · USNorth Carolina State University · USRoyal Veterinary College · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to characterize gastrointestinal (GI) transit times and pH in healthy cats.

methodsGI transit times and pH were measured in six healthy, colony-housed, purpose-bred spayed female cats using a continuous, non-invasive pH monitoring system in a sequential order design. For the first period ('pre-feeding'), food was withheld for 20 h, followed by oral administration of a pH capsule. Five hours post-capsule administration, cats were meal-fed by offering them their daily allowance of food for 1 h. For the second period ('post-feeding'), food was withheld for 24 h and cats were fed for 1 h, after which a pH capsule was orally administered. Studies in both periods were repeated three times. GI transit times and pH were compared between the two periods.

resultsThe median transit times for the pre- and post-feeding periods, respectively, were: gastric - 94 mins (range 1-4101) and 1068 mins (range 484-5521); intestinal - 1350 mins (range 929-2961) and 1534 mins (range 442-2538); and GI - 1732 mins (range 1105-5451) and 2795 mins (range 926-6563). The median GI pH values for the first and second periods, respectively, were: esophageal - 7.0 (range 3.5-7.8) and 4.5 (range 2.9-6.4); gastric - 2.7 (range 1.7-6.2) and 2.0 (range 1.1-3.3); intestinal - 8.2 (range 7.6-8.7) and 7.8 (range 6.7-8.5); first-hour small intestinal - 8.2 (range 7.4-8.7) and 8.3 (range 7.9-8.6); and last-hour large intestinal - 8.5 (range 7.0-8.9) and 7.8 (range 6.3-8.7). Gastric ( CONCLUSIONS AND RELEVANCE: Gastric and intestinal pH differed significantly when the capsule was administered 5 h prior to feeding compared with 1 h after feeding. Transit times for both periods showed high degrees of intra- and inter-individual variability.

Indexed as

Gastrointestinal TransitIntestine, SmallAdministration, OralAnimalsCatsFemaleHydrogen-Ion ConcentrationTime Factorsgastric transitintestinal transitMotilityresidence time

Identifiers

PMID34878315
PMCPMC10812322
OpenAlexW4200164842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.