Evidence map›Paper›PMID 34878303›Full record

ArticleMicrobiology spectrum2021

Plasmodium falciparum and Helminth Coinfections Increase IgE and Parasite-Specific IgG Responses.

Rebeca Santano, Rocío Rubio, Berta Grau-Pujol, Valdemiro Escola, Osvaldo Muchisse, Inocência Cuamba, Marta Vidal, Pau Cisteró, Gemma Ruiz-Olalla, Ruth Aguilar and 18 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 13 institutions in 10 countries.

Rebeca Santano *Malaria Immunology Group, ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0002-0007-5315
Rocío Rubio *Malaria Immunology Group, ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0002-0448-3404
Berta Grau-PujolMalaria Immunology Group, ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0002-7320-0965
Valdemiro EscolaCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Osvaldo MuchisseCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Inocência CuambaCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Marta VidalMalaria Immunology Group, ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Pau CisteróMalaria Immunology Group, ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Gemma Ruiz-OlallaMalaria Immunology Group, ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Ruth AguilarMalaria Immunology Group, ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Maria DemontisDepartment of Parasitology, Centre of Infectious Diseases, Leiden University Medical Centre (LUMC), Leiden, the Netherlands.
Jose Carlos JamineCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Anélsio CossaCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Charfudin SacoorCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Jorge CanoCommunicable and Non-communicable Diseases Cluster (UCN), WHO Regional Office for Africa, Brazzaville, Republic of Congo.
Luis IzquierdoMalaria Immunology Group, ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0002-3704-9874
Chetan E ChitnisMalaria Parasite Biology and Vaccines, Department of Parasites & Insect Vectors, Institut Pasteurgrid.428999.7, Paris, France.ORCID 0000-0002-8773-9865
Ross L CoppelDepartment of Microbiology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.
Virander ChauhanMalaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.
David CavanaghInstitute of Immunology and Infection Research, University of Edinburgh, Edinburgh, UK.
Sheetij DuttaWalter Reed Army Institute of Research (WRAIR), Silver Spring, Maryland, USA.
Evelina AngovWalter Reed Army Institute of Research (WRAIR), Silver Spring, Maryland, USA.
Deepak GaurMalaria Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, India.
Lisette van LieshoutDepartment of Parasitology, Centre of Infectious Diseases, Leiden University Medical Centre (LUMC), Leiden, the Netherlands.
Bin ZhanBaylor College of Medicinegrid.39382.33 (BCM), Houston, Texas, USA.
Jose MuñozMalaria Immunology Group, ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Gemma Moncunill *Malaria Immunology Group, ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Carlota Dobaño *Malaria Immunology Group, ISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0002-6751-4060
Barcelona Institute for Global Health · ESManhiça Health Research Centre · MZCentro de Investigación Biomédica en Red · ESLeiden University Medical Center · NLWalter Reed Army Institute of Research · USBaylor College of Medicine · USFundación Pro Salud y Medio Ambiente · ARInstitut Pasteur · FRInternational Centre for Genetic Engineering and Biotechnology · INJawaharlal Nehru University · INMonash University · AUUniversity of Edinburgh · GBWorld Health Organization Regional Office for Africa · CG

Funding

World Health Organization 001
6 · The paper itself

Abstract

Coinfection with Plasmodium falciparum and helminths may impact the immune response to these parasites because they induce different immune profiles. We studied the effects of coinfections on the antibody profile in a cohort of 715 Mozambican children and adults using the Luminex technology with a panel of 16 antigens from P. falciparum and 11 antigens from helminths (

Indexed as

AdolescentAdultAnimalsAntibodies, HelminthAntibodies, ProtozoanAntigens, HelminthAntigens, ProtozoanChildChild, PreschoolCoinfectionFemaleHelminthiasisHelminthsHumansImmunoglobulin EImmunoglobulin GAntibodies, HelminthAntibodies, ProtozoanAntigens, HelminthAntigens, ProtozoanImmunoglobulin EImmunoglobulin GSoilantibodiescoinfectionhelminthsIgEIgGluminexmalaria

Identifiers

PMID34878303
PMCPMC8653825
OpenAlexW4226380296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.