Evidence map›Paper›PMID 34878301›Full record

ArticleMicrobiology spectrum2021

Phenotypic Switching and Filamentation in Candida haemulonii, an Emerging Opportunistic Pathogen of Humans.

Yuchen Deng, Shuaihu Li, Jian Bing, Wanqing Liao, Li Tao

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Insights on molecular drivers of phenotypic plasticity in Candidozyma auris.World journal of microbiology & biotechnology · 2026
    Review
  3. Article
  4. Article
  5. An update on clinically relevant, rare, and emergingClinical microbiology reviews · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Control ofFuture microbiology · 2025
    Article
  11. Article
  12. Biological and genomic analyses ofNew microbes and new infections · 2024
    Article
  13. Review
  14. Article
  15. Saps1-3 Antigens inInfectious disease reports · 2024
    Article
  16. Article
  17. Review
  18. Article
  19. Zoonoses (Shannon, Ireland) · 2023
    Article
  20. Infection and drug resistance · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuchen Deng *Shanghai Key Laboratory of Molecular Medical Mycology, Department of Dermatology, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Shuaihu Li *State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan Universitygrid.8547.e, Shanghai, China.
Jian BingState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan Universitygrid.8547.e, Shanghai, China.
Wanqing LiaoShanghai Key Laboratory of Molecular Medical Mycology, Department of Dermatology, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Li TaoState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan Universitygrid.8547.e, Shanghai, China.ORCID 0000-0001-6109-3480
Fudan University · CNSecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenotypic plasticity is a common strategy adopted by fungal pathogens to adapt to diverse host environments. Candida haemulonii is an emerging multidrug-resistant human pathogen that is closely related to Candida auris. Until recently, it was assumed that C. haemulonii is incapable of phenotypic switching or filamentous growth. In this study, we report the identification of three distinct phenotypes in C. haemulonii: white, pink, and filament. The white and pink phenotypes differ in cellular size, colony morphology, and coloration on phloxine B- or CuSO

Indexed as

PhenotypeAdaptation, PhysiologicalAspartic Acid ProteasesBiological Variation, PopulationCandidaCandidiasisCopper SulfateGene Expression Regulation, FungalHot TemperatureHumansAspartic Acid ProteasesCopper SulfateCandida haemuloniifilamentous growthglycerolphenotypic switching systemtemperature dependent

Identifiers

PMID34878301
PMCPMC8653834
OpenAlexW4200011148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.