ArticleBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2021
Association of sleep disturbances with sarcopenia and its defining components: the ELSA-Brasil study.
Article in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The association between obstructive sleep apnea syndrome and sarcopenia: a meta-analysis.Frontiers in medicine · 2026Pooled it
- Restoration of circadian rhythm as novel targets against sarcopenia.Chinese medical journal · 2026Review
- Sleep-disordered breathing as a risk factor for sarcopenia in the elderly: a narrative review.Sleep & breathing = Schlaf & Atmung · 2026Review
- The role of sleep disorders in the motoric and cognitive trajectories of older physically frail sarcopenic and healthy active subjects: SOMNUS-DARE, a prospective cohort study.BMC geriatrics · 2026Article
- Couple-level obstructive sleep apnea risk and muscle health in middle- and older-aged adults.Sleep & breathing = Schlaf & Atmung · 2025Article
- Alterations in the Myokine Concentrations in Relation to Sarcopenia and Sleep Disturbances: A Narrative Review.Journal of clinical medicine · 2025Review
- Predicting Sleep Quality Based on Metabolic, Body Composition, and Physical Fitness Variables in Aged People: Exploratory Analysis with a Conventional Machine Learning Model.Journal of functional morphology and kinesiology · 2025Article
- Sleep Architecture, Muscle Function, and Daily Life Activities in Patients with Sarcopenia.Sleep science (Sao Paulo, Brazil) · 2025Article
- Associations of fat, bone, and muscle indices with disease severity in patients with obstructive sleep apnea hypopnea syndrome.Sleep & breathing = Schlaf & Atmung · 2025Article
- Sarcopenia and sleep in individuals with chronic obstructive pulmonary disease.Sleep & breathing = Schlaf & Atmung · 2024Article
- Self-Reported Sleep Duration Is a Useful Tool to Predict Sarcopenia in Chilean Older Adults: Evidence from the ALEXANDROS Longitudinal Study.Journal of personalized medicine · 2024Article
- Association Between Pain and Sarcopenia Among Adults Aged ≥65 Years from Low- and Middle-Income Countries.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcopenia and sleep problems share common physiopathology. We aimed to investigate the association of sleep disturbances with sarcopenia and its defining components in Brazilian middle-aged and older adults. In this cross-sectional analysis of the second wave of the ELSA-Brasil study, we included data from 7948 participants aged 50 years and older. Muscle mass was evaluated by bioelectrical impedance analysis and muscle strength by hand-grip strength. Sarcopenia was defined according to the Foundation for the National Institutes of Health criteria. Sleep duration and insomnia complaint were self-reported. Short sleep duration was considered as ≤6 h/night and long sleep duration as >8 h/night. High risk of obstructive sleep apnea (OSA) was assessed using the STOP-Bang questionnaire. Possible confounders included socio-demographic characteristics, lifestyle, clinical comorbidities, and use of sedatives and hypnotics. The frequencies of sarcopenia, low muscle mass, and low muscle strength were 1.6, 21.1, and 4.1%, respectively. After adjustment for possible confounders, high risk of OSA was associated with low muscle mass (OR=2.17, 95%CI: 1.92-2.45). Among obese participants, high risk of OSA was associated with low muscle strength (OR=1.68, 95%CI: 1.07-2.64). However, neither short nor long sleep duration or frequent insomnia complaint were associated with sarcopenia or its defining components. In conclusion, high risk of OSA was associated with low muscle mass in the whole sample and with low muscle strength among obese participants. Future studies are needed to clarify the temporal relationship between both conditions.
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