Evidence map›Paper›PMID 34877885›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2022

Preclinical applications of high-definition manometry system to investigate pelvic floor muscle contribution to continence mechanisms in a rabbit model.

Samuel Sorkhi, Youngjin Seo, Valmik Bhargava, Mahadevan Raj Rajasekaran

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Samuel SorkhiDepartment of Urology, University of California San Diego Medical Center, San Diego, California.
Youngjin SeoDepartment of Urology, University of California San Diego Medical Center, San Diego, California.
Valmik BhargavaDepartment of Medicine, University of California San Diego Medical Center, San Diego, California.
Mahadevan Raj RajasekaranDepartment of Urology, University of California San Diego Medical Center, San Diego, California.ORCID 0000-0003-4188-1628
University of California San Diego Medical Center · US

Funding

Aging & Urethral Sphincter Dysfunction: Role of Wnt-B Catenin Signaling PathwaysI01RX001694 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI RAJASEKARAN, MAHADEVAN RAJ · 2016 to 2020
–
RRD VA I01 RX001694
6 · The paper itself

Abstract

External anal sphincter (EAS), external urethral sphincters, and puborectalis muscle (PRM) have important roles in the genesis of anal and urethral closure pressures. In the present study, we defined the contribution of these muscles alone and in combination with the sphincter closure function using a rabbit model and a high-definition manometry (HDM) system. A total of 12 female rabbits were anesthetized and prepared to measure anal, urethral, and vaginal canal pressures using a HDM system. Pressure was recorded at rest and during electrical stimulation of the EAS and PRM. A few rabbits (

Indexed as

ManometryAnal CanalAnimalsAnus DiseasesElectric StimulationMuscle ContractionPelvic FloorPressureRabbitsexternal anal sphincterexternal urethral sphincterpuborectalis

Identifiers

PMID34877885
PMCPMC8742739
OpenAlexW4200470654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.