Evidence map›Paper›PMID 34877826›Full record

ArticleKorean circulation journal2022

Erectile Dysfunction in Men With Adult Congenital Heart Disease: A Prevalent but Neglected Issue.

Alicia Jeanette Fischer, Christin Grundlach, Paul C Helm, Ulrike Mm Bauer, Helmut Baumgartner, Gerhard-Paul Diller, German Competence Network for Congenital Heart Defects Investigators

Open access · hybridAbstract read
In one paragraph

Article in Korean circulation journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Sexual functioning after the age of 40 in adults with moderate or severe congenital heart disease.International journal of cardiology. Congenital heart disease · 2026
    Article
  2. Daily issues in the life of adults with congenital heart disease: new insights from EURO-ACHD Congress 2025.European heart journal supplements : journal of the European Society of Cardiology · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alicia Jeanette FischerDepartment of Cardiology III - Adult Congenital and Valvular Heart Disease, University Hospital Muenster, Münster, Germany. fischera@ukmuenster.de.ORCID https://orcid.org/0000-0001-6269-8895
Christin GrundlachDepartment of Cardiology III - Adult Congenital and Valvular Heart Disease, University Hospital Muenster, Münster, Germany.
Paul C HelmNational Register for Congenital Heart Defects, Berlin, Germany.ORCID https://orcid.org/0000-0002-1868-4266
Ulrike Mm BauerNational Register for Congenital Heart Defects, Berlin, Germany.ORCID https://orcid.org/0000-0001-5378-8258
Helmut BaumgartnerDepartment of Cardiology III - Adult Congenital and Valvular Heart Disease, University Hospital Muenster, Münster, Germany.ORCID https://orcid.org/0000-0002-9542-8821
Gerhard-Paul DillerDepartment of Cardiology III - Adult Congenital and Valvular Heart Disease, University Hospital Muenster, Münster, Germany.ORCID https://orcid.org/0000-0003-3050-5248
German Competence Network for Congenital Heart Defects Investigators
University Hospital Münster · DEGerman Centre for Cardiovascular Research · DE

Funding

Bundesministerium für Bildung und Forschung 01GI0601Deutsches Zentrum für Herz-KreislaufforschungEMAH Stiftung Karla Voellm, Krefeld, Germany
6 · The paper itself

Abstract

BACKGROUND AND

objectivesFor adult men with congenital heart disease (ACHD), data on erectile dysfunction (ED) is limited. We aimed to assess the frequency of ED, its role in patient-physician communication and to identify parameters predicting ED.

methodsMale ACHD ≥18 years registered at the German National Register for Congenital Heart Defects were invited to participate in an online questionnaire about sexual health. Participants with presumed ED according to International Index of Erectile Function Score were compared to patients without ED.

resultsThe 371 patients responded to the questionnaire (83% with moderate to highly complex ACHD). The 43% presented with more than mild ED. When ED was present, patients complained about general anxiety to be sexually active more often (p<0.05) and underwent sexual activity less frequently compared to those without ED (p<0.05). Age ≥40 years (odds ratio [OR], 3.04; p=0.002), being single (OR, 6.82; p<0.0001), anxiety to be sexually active (OR, 2.64; p=0.0002) and psychiatric disease (OR, 4.33; p<0.0007) emerged as independent predictors for ED. Overall, patients sought medical advice in 6.7% of cases, whilst 29.6% would appreciate an active approach by the physician to address this sensitive topic.

conclusionsED is affecting one third to one half of male ACHD according to a questionnaire-based analysis. Older age, being single, fear of sexual activity due to ACHD and psychiatric disorder emerged as independent predictors for ED. These parameters can easily be assessed to identify patients at risk. ED should be addressed proactively by health professionals.

Indexed as

CommunicationCongenital heart diseaseErectile dysfunctionQuality of lifeSexual activity

Identifiers

PMID34877826
PMCPMC8907987
OpenAlexW3212054506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.