ArticleJournal of clinical laboratory analysis2022
Malnutrition on admission increases the in-hospital mortality and length of stay in elder adults with acute ischemic stroke.
Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07628283 (A Prospective, Open-Label, Cluster Randomized Controlled Trial to Evaluate the Efficacy of a Rural Doctor-Led, Telemedicine-Supported Integrated Care Model for Reducing Cardiovascular and Cerebrovascular Events in Elderly Adults at High Risk of Stroke in China), which is not on this map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective, Open-Label, Cluster Randomized Controlled Trial to Evaluate the Efficacy of a Rural Doctor-Led, Telemedicine-Supported Integrated Care Model for Reducing Cardiovascular and Cerebrovascular Events in Elderly Adults at High Risk of Stroke in China
Who cites it
21 citing papers in PubMed, 34 citations in OpenAlex.
- Machine Learning Methods to Predict the Length of Stay for Acute Stroke: A Scoping Review and Meta-Analysis.Health care science · 2026Review
- Article
- Incremental Prognostic Value of the CONUT Score for In-Hospital Mortality and Length of Stay in Hospitalized Patients.Nutrients · 2026Observational
- Predictive value of preoperative and postoperative controlling nutritional status scores and their changes in older patients with large vessel occlusion stroke after endovascular thrombectomy.Frontiers in nutrition · 2026Article
- Superiority of pan-immune inflammation value, systemic inflammation index, and CALLY scores prognostic value for mortality of ischemic stroke patients followed in intensive care unit.BMC immunology · 2025Article
- Skeletal Muscle Mass Index and Body Fat Percentage Reflect Different Nutritional Markers Independent of BMI in Underweight Women.Nutrients · 2025Observational
- Association between the geriatric nutritional risk index and adverse post-extubation outcomes for critically ill older adults: a retrospective study.BMC pulmonary medicine · 2025Article
- The prognostic significance of malnutrition in older adult patients with acute ischemic stroke.Frontiers in nutrition · 2025Article
- Status quo, influencing factors, and association with hospitalization outcomes of malnutrition in neurological disorders in China: a national cross-sectional study.Frontiers in nutrition · 2025Article
- Neuronutrition and Its Impact on Post-Stroke Neurorehabilitation: Modulating Plasticity Through Diet.Nutrients · 2024Review
- Machine Learning and Clinical Predictors of Mortality in Cardiac Arrest Patients: A Comprehensive Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Article
- Association Between TCBI (Triglycerides, Total Cholesterol, and Body Weight Index) and Stroke-Associated Pneumonia in Acute Ischemic Stroke Patients.Clinical interventions in aging · 2024Article
- Article
- Article
- Review
- A clinical prediction model based on interpretable machine learning algorithms for prolonged hospital stay in acute ischemic stroke patients: a real-world study.Frontiers in endocrinology · 2023Article
- Impact of rehabilitation dose on body mass index change in older acute patients with stroke: a retrospective observational study.Frontiers in nutrition · 2023Article
- Review
- The Importance of Nutrition in Neurological Disorders and Nutrition Assessment Methods.Brain & NeuroRehabilitation · 2022Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeMalnutrition, as determined by the Controlling Nutritional Status (CONUT), has an effect on the 3-month and long-term prognosis of stroke patients. The association between malnutrition and in-hospital mortality has not been well established. We aimed to investigate the relationship between the CONUT score on admission and in-hospital mortality and length of stay (LOS) in elderly patients with acute ischemic stroke (AIS).
methodsThis study analyzed controls and patients with AIS. Malnutrition was determined using the CONUT score. A CONUT score of 5-12 was defined as undernutrition status. Based on the CONUT scores, the patients were divided into the low CONUT (0-4) and high CONUT (5-12) groups.
resultsIn total, 1079 participants were recruited, comprising 288 controls and 791 AIS patients. Among the 791 patients, 64 (8.1%) had malnutrition and 63 (7.9%) had an in-hospital death. Compared to the controls, the AIS patients presented higher CONUT scores, higher proportion of in-hospital mortality (8.0%), and longer length of stay. Malnutrition was independently associated with in-hospital mortality in the AIS patients (adjusted odds ratio: 3.77, 95% confidence interval [CI]: 1.55-9.15; p = 0.003). The general linear models showed an association between the CONUT score and LOS (β = 0.574, 95% CI: 0.208-0.934; p = 0.002). Furthermore, the effect of the interaction between infection and nutrition status on in-hospital mortality showed borderline statistical significance (p = 0.06).
conclusionsMalnutrition estimated by the CONUT score on admission can be a predictor of in-hospital mortality and increased LOS in elderly AIS patients.
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