Evidence map›Paper›PMID 34877706›Full record

ArticleJournal of veterinary internal medicine2022

Airway remodeling in horses with mild and moderate asthma.

Amandine Bessonnat, Pierre Hélie, Carolyn Grimes, Jean-Pierre Lavoie

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Serum Vitamin D Level Is Unchanged in Equine Asthma.Animals : an open access journal from MDPI · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Airway remodeling in horses with mild and moderate asthma.Journal of veterinary internal medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Amandine BessonnatDepartment of Clinical Sciences, Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Quebec, Canada.ORCID https://orcid.org/0000-0003-2763-2916
Pierre HélieFaculty of Veterinary Medicine, Department of Pathology and Microbiology, University of Montreal, Saint-Hyacinthe, Quebec, Canada.
Carolyn GrimesFaculty of Veterinary Medicine, Department of Pathology and Microbiology, University of Montreal, Saint-Hyacinthe, Quebec, Canada.
Jean-Pierre LavoieDepartment of Clinical Sciences, Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Quebec, Canada.ORCID https://orcid.org/0000-0003-4655-2102
Cegep de Saint Hyacinthe · CAZoetis (United States) · US

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2015-04092
6 · The paper itself

Abstract

backgroundThere is a remodeling of the central airways in horses with severe asthma but whether a similar process occurs in horses with the mild or moderate asthma (MMA) is unknown.

objectivesTo evaluate lesions affecting the central airways of horses with MMA. ANIMALS: Twelve horses with MMA and 8 control horses.

methodsCase-control retrospective study of horses classified as MMA affected or controls based on history and bronchoalveolar lavage fluid cytology. Endobronchial biopsies were analyzed using histomorphometry and a semiquantitative histologic scoring system.

resultsHistomorphometry identified epithelial hyperplasia (47 μm CONCLUSIONS AND CLINICAL RELEVANCE: Tissue remodeling of the bronchial lamina propria, epithelium, and smooth muscle was present in horses with MMA.

Indexed as

AsthmaHorse DiseasesAirway RemodelingAnimalsBronchiBronchoalveolar Lavage FluidHorsesHyperplasiaRetrospective Studiescentral airwayendobronchial biopsyhistomorphometrysemiquantitative histologic score

Identifiers

PMID34877706
PMCPMC8783337
OpenAlexW4200235095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.