ArticleJournal of the American College of Emergency Physicians open2021
Emergency department-initiated buprenorphine protocols: A national evaluation.
Article in Journal of the American College of Emergency Physicians open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- A Brief Educational Intervention to Increase ED Initiation of Buprenorphine for Opioid Use Disorder (OUD).Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2022Trial
- A Qualitative Assessment of an Electronic Health Record-Embedded Intervention to Increase In-Hospital Opioid Use Disorder Treatment Initiation.Journal of general internal medicine · 2026Article
- Emergency Department-initiated standard versus high-dose buprenorphine induction (ENVISION): a randomised clinical trial protocol.BMJ open · 2026Article
- Initiating buprenorphine in New Jersey emergency departments: a mixed methods study.JEM reports · 2026Article
- Implementation facilitation improves readiness for emergency department-initiated buprenorphine to treat opioid use disorder.Journal of substance use and addiction treatment · 2025Article
- Emergency Department Screening and Interventions for Adolescents With Substance Use: A Narrative Review.The Journal of emergency medicine · 2024Review
- Emergency department management of opioid use disorder in pediatric patients.Journal of the American College of Emergency Physicians open · 2024Article
- National Institute on Drug Abuse Clinical Trials Network Meeting Report: Advancing Emergency Department Initiation of Buprenorphine for Opioid Use Disorder.Annals of emergency medicine · 2023Article
- Precipitated opioid withdrawal after buprenorphine administration in patients presenting to the emergency department: A case series.Journal of the American College of Emergency Physicians open · 2023Article
- Emergency department-initiated buprenorphine protocols: A national evaluation.Journal of the American College of Emergency Physicians open · 2021Article
- Safety and efficacy of high dose buprenorphine initiation in fentanyl positive emergency department patients.International journal of clinical trialsArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveEmergency department-initiated buprenorphine (BUP) for opioid use disorder is an evidence-based practice, but limited data exist on BUP initiation practices in real-world settings. We sought to characterize protocols for BUP initiation among a geographically diverse sample of emergency departments (EDs).
methodsIn December 2020, we reviewed prestudy clinical BUP initiation protocols from all EDs participating in CTN0099 Emergency Department-INitiated bupreNOrphine VAlidaTION (ED-INNOVATION). We abstracted information on processes for identification of treatment-eligible patients, BUP administration, and discharge care.
resultsAll participating ED-INNOVATION sites across 22 states submitted protocols; 31 protocols were analyzed.
conclusionsIn this geographically diverse sample of EDs, protocols for ED-initiated BUP differed between sites. Future work should evaluate the association between this variation and patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.