ArticleThe Lancet regional health. Europe2021
All-cause and cause-specific mortality in people with mental disorders and intellectual disabilities, before and during the COVID-19 pandemic: cohort study.
Article in The Lancet regional health. Europe, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- The impact of the COVID-19 pandemic on mortality in people with dementia without COVID-19: a systematic review and meta-analysis.BMC geriatrics · 2022Pooled it
- Joint European policy on the COVID-19 risks for people with mental disorders: An umbrella review and evidence- and consensus-based recommendations for mental and public health.European psychiatry : the journal of the Association of European Psychiatrists · 2022Pooled it
- Disease burden of viral respiratory infections in people with intellectual disabilities: a scoping review.BMJ open respiratory research · 2026Article
- Social exclusion as a determinant of excess mortality in people with schizophrenia-spectrum and bipolar disorders: retrospective cohort study in 0.5 million people.Psychological medicine · 2025Article
- Geographic variations in end-of-life hospitalisations for patients with mental illness: a population-based observational study in England, UK.Discover mental health · 2025Article
- Article
- Age-Stratified Risk of Severe COVID-19 for People With Disabilities in Korea: Nationwide Study Considering Disability Type.Journal of Korean medical science · 2025Article
- A study of the adaptation processes of individuals with intellectual disabilities and their mothers to COVID-19 restrictions.Journal of intellectual disabilities : JOID · 2024Article
- Psychiatric adverse events following COVID-19 vaccination: a population-based cohort study in Seoul, South Korea.Molecular psychiatry · 2024Article
- Article
- Hospitalisation and mortality among privately insured individuals with COVID-19 in the United States: The role of intellectual disabilities and Neurogenetic disorders.Journal of intellectual disability research : JIDR · 2024Article
- The Impact of the Global Pandemic on Veterans with Serious Mental Illness (SMI): Healthcare Utilization and Mortality.Behavioral sciences (Basel, Switzerland) · 2024Article
- Analysis of influencing factors on long COVID in COVID-19 patients infected with omicron variant three months after discharge: a cross-sectional study.BMC infectious diseases · 2024Article
- An update of the reported effects of the COVID-19 pandemic on person with intellectual disability and their carers: a scoping review.Annals of medicine · 2023Article
- Severe mental illness, race/ethnicity, multimorbidity and mortality following COVID-19 infection: nationally representative cohort study.The British journal of psychiatry : the journal of mental science · 2023Article
- Trends in the effect of COVID-19 on consultations for persons with clinical and subclinical eating disorders.BioPsychoSocial medicine · 2023Article
- Mental-health before and during the COVID-19 pandemic in adults with neurodevelopmental disorders.Journal of psychiatric research · 2023Article
- Adverse outcomes associated with recorded victimization in mental health electronic records during the first UK COVID-19 lockdown.Social psychiatry and psychiatric epidemiology · 2023Article
- Excess deaths from COVID-19 among Medicare beneficiaries with psychiatric diagnoses: Community versus nursing home.Journal of the American Geriatrics Society · 2023Article
- Significant regional inequalities in the prevalence of intellectual disability and trends from 1990 to 2019: a systematic analysis of GBD 2019.Epidemiology and psychiatric sciences · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPeople with mental disorders and intellectual disabilities experience excess mortality compared with the general population. The impact of COVID-19 on exacerbating this, and in widening ethnic inequalities, is unclear.
methodsProspective data (N=167,122) from a large mental healthcare provider in London, UK, with deaths from 2019 to 2020, used to assess age- and gender-standardised mortality ratios (SMRs) across nine psychiatric conditions (schizophrenia-spectrum disorders, affective disorders, somatoform/ neurotic disorders, personality disorders, learning disabilities, eating disorders, substance use disorders, pervasive developmental disorders, dementia) and by ethnicity.
findingsPrior to the World Health Organization (WHO) declaring COVID-19 a public health emergency on 30th January 2020, all-cause SMRs across all psychiatric cohorts were more than double the general population. By the second quarter of 2020, when the UK experienced substantial peaks in COVID-19 deaths, all-cause SMRs increased further, with COVID-19 SMRs elevated across all conditions (notably: learning disabilities: SMR: 9.24 (95% CI: 5.98-13.64), pervasive developmental disorders: 5.01 (95% CI: 2.40-9.20), eating disorders: 4.81 (95% CI: 1.56-11.22), schizophrenia-spectrum disorders: 3.26 (95% CI: 2.55-4.10), dementia: 3.82 (95% CI: 3.42, 4.25) personality disorders 4.58 (95% CI: 3.09-6.53)). Deaths from other causes remained at least double the population average over the whole year. Increased SMRs were similar across ethnic groups.
interpretationPeople with mental disorders and intellectual disabilities were at a greater risk of deaths relative to the general population before, during and after the first peak of COVID-19 deaths, with similar risks by ethnicity. Mortality from non-COVID-19/ other causes was elevated before/ during the pandemic, with higher COVID-19 mortality during the pandemic.
fundingESRC (JD, CM), NIHR (JD, RS, MH), Health Foundation (JD), GSK, Janssen, Takeda (RS).
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Registered trials
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