Evidence map›Paper›PMID 34877518›Full record

ArticleEpilepsy & behavior reports2021

Atypical presentation of

Spoorthi Jagadish, Lillian Howard, Sreenath Thati Ganganna

Open access · goldAbstract readCase Reports
In one paragraph

Article in Epilepsy & behavior reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Removal of Toxic Metabolites-Chelation: Manganese Disorders.Journal of inherited metabolic disease · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Spoorthi JagadishDepartment of Pediatric Neurology, University of Iowa, United States.
Lillian HowardDepartment of Pediatric Neurology, University of Iowa, United States.
Sreenath Thati GangannaDepartment of Pediatric Neurology, University of Iowa, United States.
University of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Manganese is an essential element that is ubiquitously present in our diet and water supply. It is a cofactor for several critical physiological processes. Elevated blood levels of Manganese secondary to

Indexed as

ADHD, attention deficit hyperactivity disorderALT, alanine transaminaseAST, aspartate transaminaseCBC, complete blood countDystoniaEEG, electroencephalogramHypermanganesemiaMCHC, mean corpuscular hemoglobin concentrationMCH, mean corpuscular hemoglobinMCV, mean corpuscular volumeMn, ManganeseMRI, magnetic resonance imagingPolycythemiaRDW, red cell distribution widthSeizuresSLC30A10 gene mutationT1 hyperintensityTIBC, total iron binding capacity

Identifiers

PMID34877518
PMCPMC8633869
OpenAlexW3212293206

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.