Evidence map›Paper›PMID 34877473›Full record

ArticleIntegrative organismal biology (Oxford, England)2021

Environmental Thermal Stress Induces Neuronal Cell Death and Developmental Malformations in Reptiles.

Thomas J Sanger, Laura Harding, Judith Kyrkos, Alexandrea J Turnquist, Lilian Epperlein, Sylvia A Nunez, Dryden Lachance, Seerat Dhindsa, James T Stroud, Raul E Diaz and 1 more

Open access · goldAbstract read
In one paragraph

Article in Integrative organismal biology (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Thomas J SangerDepartment of Biology, Loyola University Chicago, 1050 Sheridan Rd., Chicago, IL 60660, USA.ORCID https://orcid.org/0000-0003-0047-1884
Laura HardingDepartment of Biology, Loyola University Chicago, 1050 Sheridan Rd., Chicago, IL 60660, USA.
Judith KyrkosDepartment of Biology, Loyola University Chicago, 1050 Sheridan Rd., Chicago, IL 60660, USA.
Alexandrea J TurnquistDepartment of Biology, Loyola University Chicago, 1050 Sheridan Rd., Chicago, IL 60660, USA.
Lilian EpperleinDepartment of Biology, Loyola University Chicago, 1050 Sheridan Rd., Chicago, IL 60660, USA.
Sylvia A NunezDepartment of Biology, Loyola University Chicago, 1050 Sheridan Rd., Chicago, IL 60660, USA.
Dryden LachanceDepartment of Biology, Loyola University Chicago, 1050 Sheridan Rd., Chicago, IL 60660, USA.
Seerat DhindsaDepartment of Biology, Loyola University Chicago, 1050 Sheridan Rd., Chicago, IL 60660, USA.
James T StroudDepartment of Biology, Washington University in St. Louis, Campus Box 1137. One Brookings Drive St. Louis, MO 63130-4899, USA.ORCID https://orcid.org/0000-0003-0734-6795
Raul E DiazDepartment of Biological Sciences, California State University, Los Angeles, 5151 State University Dr., Los Angeles, CA 90032, USA.
Beata CzesnyDepartment of Biology, Loyola University Chicago, 1050 Sheridan Rd., Chicago, IL 60660, USA.
Loyola University Chicago · USCalifornia State University Los Angeles · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Every stage of organismal life history is being challenged by global warming. Many species are already experiencing temperatures approaching their physiological limits; this is particularly true for ectothermic species, such as lizards. Embryos are markedly sensitive to thermal insult. Here, we demonstrate that temperatures currently experienced in natural nesting areas can modify gene expression levels and induce neural and craniofacial malformations in embryos of the lizard

Identifiers

PMID34877473
PMCPMC8643577
OpenAlexW3214863940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.