Evidence map›Paper›PMID 34877437›Full record

ArticleNeurobiology of pain (Cambridge, Mass.)

Input-dependent synaptic suppression by pregabalin in the central amygdala in male mice with inflammatory pain.

Sumii Yamamoto, Yukari Takahashi, Fusao Kato

Open access · goldAbstract read
In one paragraph

Article in Neurobiology of pain (Cambridge, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  6. Voltage-gated calcium channel subunit αFrontiers in molecular neuroscience · 2023
    Article
  7. Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sumii YamamotoDepartment of Anesthesiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.
Yukari TakahashiDepartment of Neuroscience, The Jikei University School of Medicine, Minato, Tokyo 105-8461, Japan.
Fusao KatoDepartment of Neuroscience, The Jikei University School of Medicine, Minato, Tokyo 105-8461, Japan.
Jikei University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregabalin (PGB) is a synthetic amino acid compound most widely prescribed for chronic peripheral and central neuropathic pain. PGB is a ligand for the α

Indexed as

BLA, basolateral amygdalaCeA, central nucleus of the amygdalaCeC/L, capsular and lateral part of the central nucleus of the amygdalaCentral amygdalaEPSC, Excitatory postsynaptic currentFormalin modelLatent inflammatory painLPB, parabrachial nucleusPGB, pregabalinPPR, paired-pulse ratioPregabalinSynaptic transmissionVDCC, voltage-dependent Ca2+ channel

Identifiers

PMID34877437
PMCPMC8628014
OpenAlexW3216733537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.