Evidence map›Paper›PMID 34877362›Full record

ArticleOpen forum infectious diseases2021

A Qualitative Study of the Experience of Immediate Antiretroviral Therapy Among Urban Persons With Newly Diagnosed Human Immunodeficiency Virus.

Katerina A Christopoulos, Xavier A Erguera, Lyndon VanderZanden, Chadwick Campbell, Maya Green, Manami Diaz Tsuzuki, John Schneider, Susa Coffey, Oliver Bacon, Monica Gandhi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Observational
  2. Observational
  3. Effective Messages to Reduce Stigma among People Newly Diagnosed with HIV during Rapid ART Initiation.International journal of environmental research and public health · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Katerina A ChristopoulosUniversity of California, San Francisco, San Francisco, California, USA.
Xavier A ErgueraUniversity of California, San Francisco, San Francisco, California, USA.
Lyndon VanderZandenHoward Brown Health, Chicago, Illinois, USA.
Chadwick CampbellUniversity of California, San Francisco, San Francisco, California, USA.
Maya GreenHoward Brown Health, Chicago, Illinois, USA.
Manami Diaz TsuzukiUniversity of California, San Francisco, San Francisco, California, USA.
John SchneiderHoward Brown Health, Chicago, Illinois, USA.
Susa CoffeyUniversity of California, San Francisco, San Francisco, California, USA.
Oliver BaconUniversity of California, San Francisco, San Francisco, California, USA.
Monica GandhiUniversity of California, San Francisco, San Francisco, California, USA.
Kimberly A KoesterUniversity of California, San Francisco, San Francisco, California, USA.
University of California, San Francisco · USHoward Brown Health Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGuidelines recommend immediate antiretroviral therapy (ART) at or shortly after human immunodeficiency virus (HIV) diagnosis, yet little is known about how people living with HIV (PLWH) experience this treatment strategy, including racial/ethnic minorities, cisgender/transgender women, and those with housing instability.

methodsTo assess the acceptability of immediate ART offer among urban PLWH, understand how this approach affects the lived experience of HIV diagnosis, and explore reasons for declining immediate ART, we conducted a cross-sectional qualitative study using semi-structured interviews with individuals who had been offered immediate ART after HIV diagnosis at a safety-net HIV clinic in San Francisco and a federally qualified health center in Chicago. Interviews were analyzed using thematic analysis.

resultsAmong 40 participants with age range 19-52 years, 27% of whom were cisgender/transgender women or gender-queer, 85% racial/ethnic minority, and 45% homeless/unstably housed, we identified 3 major themes: (1) Individuals experienced immediate ART encounters as supportive; (2) individuals viewed immediate ART as sensible; and (3) immediate ART offered emotional relief by offsetting fears of death and providing agency over one's health. Reasons for declining immediate ART ranged from simply needing a few more days to complex interactions of logistical and psychosocial barriers.

conclusionsImmediate ART was highly acceptable to urban persons with newly diagnosed HIV infection. Immediate ART was viewed as a natural next step after HIV diagnosis and provided a sense of control over one's health, mitigating anxiety over a decline in physical health. As such, immediate ART somewhat eased but in no way obviated the psychosocial challenges of HIV diagnosis.

Indexed as

early ARTHIV testingimmediate ARTlinkage to careRAPID ARTretention in care

Identifiers

PMID34877362
PMCPMC8643677
OpenAlexW3199473516

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.