Evidence map›Paper›PMID 34877061›Full record

ArticleSurgical neurology international2021

Clinical outcome of selective amygdalectomy in a series of patients with resistant temporal lobe epilepsy.

Guive Sharifi, Mohammad Hallajnejad, Samaneh Sadat Dastgheib, Mahmoud Lotfinia, Omidvar Rezaei Mirghaed, Arsalan Medical Amin

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Surgical neurology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Exacerbation of restless legs syndrome following amygdalohippocampectomy: A case report.PCN reports : psychiatry and clinical neurosciences · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Guive SharifiDepartment of Neurosurgery, Skull Base Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran.
Mohammad HallajnejadDepartment of Neurosurgery, Skull Base Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran.
Samaneh Sadat DastgheibDepartment for General Psychology and Cognitive Neuroscience, Friedrich Schiller University of Jena, Jena, Thuringia.
Mahmoud LotfiniaDepartment of Neurosurgery, Klinikum Saarbrücken, University of Saarland, Saarbrücken, Saarland, Germany.
Omidvar Rezaei MirghaedDepartment of Neurosurgery, Skull Base Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran.
Arsalan Medical AminDepartment of Neurosurgery, Skull Base Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran.
Shahid Beheshti University · IRFriedrich Schiller University Jena · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelective amygdalohippocampectomy is one of the main approaches for treating medial temporal lobe epilepsy (TLE). We herewith describe seven cases of amygdala lesions treated with selective amygdalectomy with the hippocampus saving procedure. Furthermore, we explain the trans-middle temporal gyrus transventricular approach for selective amygdalectomy.

methodsWe studied patients with TLE who underwent selective amygdalectomy with hippocampal saving procedure between March 2012 and July 2018. We preferred the trans-middle temporal gyrus transventricular approach. We adopted pterional craniotomy with extensive exposure of the base and posterior of the temporal lobe. The posterior margin of resection in the intraventricular part of the amygdala was considered the inferior choroidal point. Medially anterior part of the uncus was resected until reaching the ambient cistern. We applied the transcortical transventricular approach for selective amygdalectomy in all patients.

resultsWe present 11 cases having an amygdala lesion in our series, seven of whom underwent selective amygdalectomy with hippocampal sparing. Nine patients had neoplastic lesions, and in two of them, gliosis was evident. Total resection of the lesion was achieved in all cases based on postoperative magnetic resonance imaging. No unusual complication or surgically-related new neurological deficit occurred.

conclusionWe consider the resection of the amygdala until the inferior choroidal point sufficient for the disconnection of its circuits, which results in more effective control of seizures and reduction of surgery time and complications.

Indexed as

AmygdalaAmygdalectomyCase seriesClinical outcomeMedial temporal lobe epilepsy

Identifiers

PMID34877061
PMCPMC8645478
OpenAlexW3214888612

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.