Evidence map›Paper›PMID 34877012›Full record

ArticleObesity science & practice2021

Traditional and novel cardiometabolic risk markers across strata of body mass index in young adults.

Mia Klinkvort Kempel, Trine Nøhr Winding, Vibeke Lynggaard, Steven Brantlov, Johan Hviid Andersen, Morten Böttcher

Open access · goldAbstract read
In one paragraph

Article in Obesity science & practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mia Klinkvort KempelDepartment of Occupational Medicine - University Research Clinic Danish Ramazzini Centre Regional Hospital West Jutland Herning Denmark.ORCID https://orcid.org/0000-0003-1669-5110
Trine Nøhr WindingDepartment of Occupational Medicine - University Research Clinic Danish Ramazzini Centre Regional Hospital West Jutland Herning Denmark.
Vibeke LynggaardCardiovascular Research Unit Department of Cardiology Gødstrup Hospital Herning Denmark.
Steven BrantlovDepartment of Procurement and Clinical Engineering Central Denmark Region Aarhus Denmark.
Johan Hviid AndersenDepartment of Occupational Medicine - University Research Clinic Danish Ramazzini Centre Regional Hospital West Jutland Herning Denmark.
Morten BöttcherCardiovascular Research Unit Department of Cardiology Gødstrup Hospital Herning Denmark.
Regional Hospital West Jutland · DKGlostrup Hospital · DKCentral Denmark Region · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiometabolic risk increases with increasing body mass index (BMI). The exact mechanism is poorly understood, and traditional risk assessment of young adults with obesity has shown to be ineffective. Greater knowledge about potential new effective biomarkers and the use of advanced cardiac imaging for risk assessment in young adults is, therefore, necessary.

objectiveThis study aims to explore traditional and novel cardiometabolic risk markers across strata of BMI in young adults.

methodsParticipants (

resultsNo significant coronary artery calcifications were detected in this study. Minor differences in median levels of traditional risk markers were detected across BMI-strata, for example, total cholesterol (men- NW: 4.7 (4.3-5.1) and OB: 4.8 (4.2-5.6) mmol/L,

conclusionIn young adults, obesity is associated with an early onset insulin resistance and inflammatory response prior to development of coronary artery calcification and deterioration of lipid profiles.

Indexed as

body mass indexcardiovascular riskinflammationobesityrisk management

Identifiers

PMID34877012
PMCPMC8633932
OpenAlexW3162592879

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.