Evidence map›Paper›PMID 34876946›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2021

Transcriptional Response of Multidrug-Resistant

Roman Farooq Alvi, Bilal Aslam, Muhammad Hidayat Rasool, Saima Muzammil, Abu Baker Siddique, Nafeesa Yasmeen, Mohsin Khurshid, Noreen Sarwar, Ahmad Almatroudi, Riaz Hussain and 1 more

Open access · goldAbstract read
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. [Clinical and molecular characteristics of neonatalZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Article
  2. Article
  3. Distribution ofInfection and drug resistance · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Roman Farooq AlviDepartment of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan.
Bilal AslamDepartment of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan.ORCID https://orcid.org/0000-0002-5568-5049
Muhammad Hidayat RasoolDepartment of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan.ORCID https://orcid.org/0000-0002-6324-1798
Saima MuzammilDepartment of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan.ORCID https://orcid.org/0000-0002-7775-8878
Abu Baker SiddiqueDepartment of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan.ORCID https://orcid.org/0000-0002-8589-2292
Nafeesa YasmeenCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 610642, China.
Mohsin KhurshidDepartment of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan.ORCID https://orcid.org/0000-0002-3196-2857
Noreen SarwarInstitute of Microbiology, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Ahmad AlmatroudiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia.ORCID https://orcid.org/0000-0002-1491-6402
Riaz HussainUniversity College of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Zulqarnain BalochFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan 650500, China.ORCID https://orcid.org/0000-0002-7873-1343
Government College University, Faisalabad · PKIslamia University of Bahawalpur · PKKunming University of Science and Technology · CNQassim University · SASouth China Agricultural University · CNUniversity of Veterinary and Animal Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe term "persisters" refers to a small bacterial population that persists during treatment with high antibiotic concentration or dose in the absence of genetic resistance. The present study was designed to investigate the transcriptional response in indigenous

methodsIsolation and identification of

resultsAmong 34 isolates, 23 (67%) were resistant to ciprofloxacin. Both QRDR (

conclusionThe transcriptional response revealed the upregulation of DNA repair and protein folding elements (

Identifiers

PMID34876946
PMCPMC8645360
OpenAlexW3215938329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.