Evidence map›Paper›PMID 34876907›Full record

ArticleStem cells international2021

Cytological Effects of Serum Isolated from Polytraumatized Patients on Human Bone Marrow-Derived Mesenchymal Stem Cells.

Yazhou Long, Katrin Bundkirchen, Pascal Gräff, Christian Krettek, Sandra Noack, Claudia Neunaber

Abstract read
In one paragraph

Article in Stem cells international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yazhou LongTrauma Department, Hannover Medical School, 30625 Hannover, Germany.ORCID https://orcid.org/0000-0003-0262-1444
Katrin BundkirchenTrauma Department, Hannover Medical School, 30625 Hannover, Germany.ORCID https://orcid.org/0000-0002-5256-3732
Pascal GräffTrauma Department, Hannover Medical School, 30625 Hannover, Germany.ORCID https://orcid.org/0000-0001-5458-6391
Christian KrettekTrauma Department, Hannover Medical School, 30625 Hannover, Germany.ORCID https://orcid.org/0000-0001-9807-0020
Sandra NoackTrauma Department, Hannover Medical School, 30625 Hannover, Germany.ORCID https://orcid.org/0000-0002-5880-7611
Claudia NeunaberTrauma Department, Hannover Medical School, 30625 Hannover, Germany.ORCID https://orcid.org/0000-0002-8537-2238

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to their immunomodulatory and regenerative capacity, human bone marrow-derived mesenchymal stem cells (hBMSCs) are promising in the treatment of patients suffering from polytrauma. However, few studies look at the effects of sera from polytraumatized patients on hBMSCs. The aim of this study was to explore changes in hBMSC properties in response to serum from polytrauma patients taken at different time points after the trauma incident. For this, sera from 84 patients with polytrauma (collected between 2010 and 2020 in our department) were used. In order to test the differential influence on hBMSC, sera from the 1

Identifiers

PMID34876907
PMCPMC8645412

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.