Evidence map›Paper›PMID 34876865›Full record

ArticleNature and science of sleep2021

Automatic Sleep Stage Classification of Children with Sleep-Disordered Breathing Using the Modularized Network.

Huijun Wang, Guodong Lin, Yanru Li, Xiaoqing Zhang, Wen Xu, Xingjun Wang, Demin Han

Open access · goldAbstract read
In one paragraph

Article in Nature and science of sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Deep Learning in Otolaryngology: A Narrative Review.JAMA otolaryngology-- head & neck surgery · 2026
    Review
  3. Temporally Continuous Automated Sleep-Wake Classification Using Deep Learning.medRxiv : the preprint server for health sciences · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Evaluation of automated pediatric sleep stage classification using U-Sleep: a convolutional neural network.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  8. An electroencephalography-based sleep index and supervised machine learning as a suitable tool for automated sleep classification in children.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Huijun Wang *Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China.
Guodong Lin *Department of Electronic Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, People's Republic of China.
Yanru LiDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China.
Xiaoqing ZhangDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China.
Wen XuDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China.
Xingjun WangDepartment of Electronic Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, People's Republic of China.
Demin HanDepartment of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China.
Capital Medical University · CNTsinghua University · CNBeijing Tongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop an automatic sleep stage analysis model for children and evaluate the effect of the model on the diagnosis of sleep-disordered breathing (SDB). PATIENTS AND

methodsThree hundred and forty-four SDB patients aged between 2 to 18 years who completed polysomnography (PSG) to assess the severity of the disease were enrolled in this study. We developed deep neural networks to stage sleep from electroencephalography (EEG), electrooculography (EOG) and electromyogram (EMG). The model performance was estimated by accuracy, precision, recall, F1-score, and Cohen's Kappa coefficient (ĸ). And we compared the difference in calculation of sleep parameters among the technicians, the model ensemble, and the single-channel EEG model.

resultsThe numbers of raw data divided into training, validation, and testing were 240, 36, and 68, respectively. The best performance appeared in the model ensemble of which the accuracy was 83.36% (ĸ=0.7817) in 5-stages, and the accuracy was 96.76% (ĸ=0.8236) in 2-stages. The single-channel EEG model showed the classification satisfyingly as well. There was no significant difference in TST, SE, SOL, time in W, time in N1+N2, time in N3, and OAHI between technician and the model (P>0.05). On the datasets from sleep-EDF-13 and sleep-EDF-18, the average classification accuracies achieved were 92.76% and 91.94% in 5-stages by using the proposed method, respectively.

conclusionThis research established the model for pediatric automatic sleep stage classification with satisfying reliability and generalizability. In addition, it could be applied for calculating quantitative sleep parameters and evaluating the severity of SDB.

Indexed as

childrendeep learningSDBsleep-disordered breathingsleep stage

Identifiers

PMID34876865
PMCPMC8643215
OpenAlexW3217139813

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.