ArticleClinical ophthalmology (Auckland, N.Z.)2021
Regional Distribution of Choroidal Thickness and Diurnal Variation in Choroidal Thickness and Axial Length in Young Adults.
Article in Clinical ophthalmology (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 22 citations in OpenAlex.
- Effect of 0.01% Atropine on Choroidal Thickness and Ocular Growth in Pre-myopic Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Trial
- Assessing acute nicotine impact on choroidal thickness: a randomized, double-blinded study comparing smoking cessation aids, including nicotine gum and electronic cigarettes.International ophthalmology · 2024Trial
- OCT-guided angle-resolved low-coherence interferometry for microstructural analysis of the human retina.Biomedical optics express · 2026Article
- Indocyanine green angiography and machine learning analysis determine topographic distribution of peripheral hard drusen in a Chinese cohort.Communications medicine · 2026Article
- Impact of Myopia Control Spectacle Lenses on Visual Functions in Young Adults: A Comprehensive Evaluation.Journal of clinical medicine · 2026Article
- The Acute Effects of Caffeine on OCT and OCTA Parameters: A Systematic Review and Meta-Analysis.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Choroidal Thickness and Postural Stability in Young Adults: Exploring Ocular Contributions to Balance and Fall Prevention.Journal of multidisciplinary healthcare · 2026Article
- Evaluation of choroidal thickness, choroidal vascular diameter, choroidal vascularity index, their correlations, and interocular symmetry in a healthy population.International ophthalmology · 2025Article
- Corneal higher-order aberrations as key predictive indicators of axial elongation in myopic children with orthokeratology: a single-center prospective cohort study.Scientific reports · 2025Article
- Article
- Choroidal response to optical defocus as a potential surrogate marker for myopia control effect.International journal of ophthalmology · 2025Article
- Diurnal Variation in Choroidal Parameters Among Healthy Subjects Using Wide-Field Swept-Source Optical Coherence Tomography Angiography.Translational vision science & technology · 2024Article
- Impact of multifocal gas-permeable lens designs on short-term choroidal response, axial length, and retinal defocus profile.International journal of ophthalmology · 2024Article
- Efficacy of small back optic zone design on myopia control for corneal refractive therapy (CRT): a one-year prospective cohort study.Eye and vision (London, England) · 2023Article
- Ophthalmologic Phenotype-Genotype Correlations in Patients With Oculocutaneous Albinism Followed in a Reference Center.Investigative ophthalmology & visual science · 2023Observational
- Thicknesses of the retina and choroid in children with retinitis pigmentosa.BMC ophthalmology · 2023Article
- Choroidal thickness measurements in young Saudi adult population: a cross-sectional study.International journal of ophthalmology · 2023Article
- Within-day changes in luminal, stromal choroidal thickness, and choroidal vascularity index in healthy adults.Indian journal of ophthalmology · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo examine the regional distribution of choroidal thickness (ChT) and the diurnal variation in ChT and axial length (AL) over a wide range of myopic refractive error.
methodsChT was measured in thirty-four healthy young adults (age mean ± SD: 25.2 ± 2.8, range: 18-35 years) using spectral-domain optical coherence tomography and AL using an IOL-Master 500. Participants were divided into three refractive groups: emmetropes, myopes, and high myopes. We evaluated ChT in macular (foveal, parafovea, and perifovea) and peripheral regions (6-mm from the foveal pit) in four quadrants (superior, temporal, inferior, and nasal). To assess the diurnal variation, three measurement sessions of ChT and AL were taken at 8 AM, 12 PM, 4 PM.
resultsChT thins progressively towards the periphery. Superior and nasal quadrants exhibited the thickest (277 ± 73 µm) and thinnest (218 ± 89 µm) choroid, respectively. Higher myopic eyes showed an overall thinner choroid (237 ± 48 µm) compared to myopic eyes (264 ± 78 µm) (P < 0.05). Higher myopes exhibited a significant choroidal thinning in all quadrants except in the temporal quadrant (all p < 0.05). Both ChT and AL underwent a significant diurnal variation (p < 0.05). The ChT and AL diurnal variation amplitudes in higher myopes were significantly reduced (ChT: 14.6 ± 11, AL: 14.5 ± 13 µm), compared to those in emmetropes (ChT: 21.4 ± 15, AL: 21.3 ± 8.5 µm) and myopes (ChT: 19 ± 17, AL: 19 ± 9.7 µm). Diurnal variation amplitude in ChT did not differ significantly across quadrants and choroidal eccentricity regions (p > 0.05).
conclusionChT distribution varies based on quadrant and eccentricity; superior choroid exhibited the thickest, and nasal showed the thinnest choroid. Higher myopes experience a reduced diurnal variation in ChT and AL.
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