Evidence map›Paper›PMID 34876791›Full record

ArticleWorld journal of gastroenterology2021

Yung-Yu Hsieh, Shui-Yi Tung, Hung-Yu Pan, Te-Sheng Chang, Kuo-Liang Wei, Wei-Ming Chen, Yi-Fang Deng, Chung-Kuang Lu, Yu-Hsuan Lai, Cheng-Shyong Wu and 1 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Metaplasia Enables Stomach Colonization bybioRxiv : the preprint server for biology · 2025
    Article
  6. Review
  7. Article
  8. MedComm · 2025
    Review
  9. Periodontal Status and Gingival Crevicular FluidJournal of clinical medicine · 2025
    Article
  10. International journal of molecular sciences · 2025
    Review
  11. Review
  12. Microbiota and gastric cancer: from molecular mechanisms to therapeutic strategies.Frontiers in cellular and infection microbiology · 2025
    Review
  13. Article
  14. Review
  15. Structural aspects of CEACAM1 interactions.European journal of clinical investigation · 2024
    Review
  16. World journal of gastroenterology · 2024
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yung-Yu HsiehDepartment of Gastroenterology and Hepatology, Chiayi Chang Gung Memorial Hospital, Chiayi 61301, Taiwan.
Shui-Yi TungDepartment of Gastroenterology and Hepatology, Chiayi Chang Gung Memorial Hospital, Chiayi 61301, Taiwan.
Hung-Yu PanDepartment of Applied Mathematics, National Chiayi University, Chiayi 60035, Taiwan.
Te-Sheng ChangDepartment of Gastroenterology and Hepatology, Chiayi Chang Gung Memorial Hospital, Chiayi 61301, Taiwan.
Kuo-Liang WeiDepartment of Gastroenterology and Hepatology, Chiayi Chang Gung Memorial Hospital, Chiayi 61301, Taiwan.
Wei-Ming ChenDepartment of Gastroenterology and Hepatology, Chiayi Chang Gung Memorial Hospital, Chiayi 61301, Taiwan.
Yi-Fang DengDepartment of Gastroenterology and Hepatology, Chiayi Chang Gung Memorial Hospital, Chiayi 61301, Taiwan.
Chung-Kuang LuDepartment of Gastroenterology and Hepatology, Chiayi Chang Gung Memorial Hospital, Chiayi 61301, Taiwan.
Yu-Hsuan LaiDepartment of Gastroenterology and Hepatology, Chiayi Chang Gung Memorial Hospital, Chiayi 61301, Taiwan.
Cheng-Shyong WuDepartment of Gastroenterology and Hepatology, Chiayi Chang Gung Memorial Hospital, Chiayi 61301, Taiwan.
Chin LiDepartment of Biomedical Sciences, National Chung Cheng University, Chiayi 62130, Taiwan. biocl@ccu.edu.tw.
Chiayi Chang Gung Memorial Hospital · TWNational Chiayi University · TWNational Chung Cheng University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn increased amount of

aimTo identify

methodsCoculture of

resultsRNA sequencing and subsequent pathway analysis revealed a drastic interferon response induced by a high colonization load. This response peaked within 24 h and subsided after 72 h of incubation. In contrast, deregulation of actin and its regulators was observed during prolonged incubation under a low colonization load, likely altering the mobility of gastric cancer cells. According to the clinical specimen analysis, approximately one-third of the gastric cancer patients were positive for

conclusion

Indexed as

Colorectal NeoplasmsFusobacterium InfectionsHelicobacter pyloriStomach NeoplasmsFusobacterium nucleatumHumansFusobacterium nucleatumGastric cancerHelicobacter pyloriInterferonMobilitySurvival

Identifiers

PMID34876791
PMCPMC8611209
OpenAlexW3211497332

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.