SynthesisBritish journal of sports medicine2022
Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies.
Synthesis in British journal of sports medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Physical activity is associated with lower mortality in adults with obesity: a systematic review with meta-analysis.BMC public health · 2024Pooled it
- The COVID-19 Pandemic and Daily Steps in the General Population: Meta-analysis of Observational Studies.JMIR public health and surveillance · 2023Pooled it
- Metabolic profile in women with bulimia nervosa or binge-eating disorder before and after treatment: secondary analysis from the randomized PED-t trial.Eating and weight disorders : EWD · 2023Trial
- Non-Vigorous Physical Activity Associated with Reduced Hospitalization Risk with or without Diabetes or Peripheral Artery Disease: Study of Latinos.Medicine and science in sports and exercise · 2026Article
- Global burden of chronic kidney disease due to diabetes mellitus type 2 attributable to low physical activity and high body mass index from 1990 to 2021.Biology of sport · 2025Article
- Accelerometer-derived "weekend warrior" physical activity, sedentary behavior, and risk of dementia.Alzheimer's research & therapy · 2025Article
- WHO guidelines on waist circumference and physical activity and their joint association with cancer risk.British journal of sports medicine · 2025Article
- Association between physical activity levels and mortality across adiposity: A longitudinal study of age-specific Asian populations.Geriatrics & gerontology international · 2024Article
- Genetic Liability to Cardiovascular Disease, Physical Activity, and Mortality: Findings from the Finnish Twin Cohort.Medicine and science in sports and exercise · 2024Article
- Physical Activity Levels in Transplant Recipients.Annals of transplantation · 2024Article
- Physical Activity, Cardiovascular Status, Mortality, and Prediabetes in Hispanic and Non-Hispanic Adults.JAMA network open · 2024Article
- Dose-response associations, physical activity intensity and mortality risk: A narrative review.Journal of sport and health science · 2024Review
- Secular trends of cardiorespiratory fitness in children and adolescents over a 35-year period: Chronicle of a predicted foretold.Frontiers in public health · 2022Article
- Accelerometer-derived physical activity and sedentary behaviors in individuals with newly diagnosed type 2 diabetes: A cross-sectional study from the Danish nationwide DD2 cohort.Frontiers in sports and active living · 2022Article
Corrections and comments
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Authors and funding
24 authors.
Funding
Abstract
backgroundThe joint associations of total and intensity-specific physical activity with obesity in relation to all-cause mortality risk are unclear.
methodsWe included 34 492 adults (72% women, median age 62.1 years, 2034 deaths during follow-up) in a harmonised meta-analysis of eight population-based prospective cohort studies with mean follow-up ranging from 6.0 to 14.5 years. Standard body mass index categories were cross-classified with sample tertiles of device-measured total, light-to-vigorous and moderate-to-vigorous physical activity and sedentary time. In five cohorts with waist circumference available, high and low waist circumference was combined with tertiles of moderate-to-vigorous physical activity.
resultsThere was an inverse dose-response relationship between higher levels of total and intensity-specific physical activity and mortality risk in those who were normal weight and overweight. In individuals with obesity, the inverse dose-response relationship was only observed for total physical activity. Similarly, lower levels of sedentary time were associated with lower mortality risk in normal weight and overweight individuals but there was no association between sedentary time and risk of mortality in those who were obese. Compared with the obese-low total physical activity reference, the HRs were 0.59 (95% CI 0.44 to 0.79) for normal weight-high total activity and 0.67 (95% CI 0.48 to 0.94) for obese-high total activity. In contrast, normal weight-low total physical activity was associated with a higher risk of mortality compared with the obese-low total physical activity reference (1.28; 95% CI 0.99 to 1.67).
conclusionsHigher levels of physical activity were associated with lower risk of mortality irrespective of weight status. Compared with obesity-low physical activity, there was no survival benefit of being normal weight if physical activity levels were low.
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