Observational studyAdvances in rheumatology (London, England)2021
Cardiac magnetic resonance imaging in patients with Behçet's disease.
Observational study in Advances in rheumatology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 6 citations in OpenAlex.
- Echocardiographic characteristics and clinical features of cardiac involvement in Behçet's disease: a retrospective single-center case series.Quantitative imaging in medicine and surgery · 2026Article
- Increased Corrected Index of Cardiac Electrophysiological Balance in Behçet's Disease: Association with Disease Duration.Journal of clinical medicine · 2026Article
- Cardiac involvement in Behçet's syndrome: findings from a clinically driven cardiological evaluation.Rheumatology (Oxford, England) · 2026Article
- Right ventricular outflow tract thrombus associated with pulmonary embolism in Behçet's syndrome.Radiology case reports · 2026Article
- Case report: Pediatric vascular Behçet's disease with prominent arterial involvement: a case series of five patients.Frontiers in immunology · 2026Article
- Cardiac Manifestations in Behçet's Syndrome.Current rheumatology reports · 2025Review
- Cardiac involvement in a female patient with Beçhet's disease: newer diagnostic and therapeutic approaches-a case report.European heart journal. Case reports · 2024Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBehçet's disease (BD) is a multisystemic vasculitis that may affect the heart. However, the incidence and nature of cardiac involvement in BD have not been clearly documented yet. The aim of this study was to delineate the cardiac magnetic resonance imaging (MRI) appearances of cardiac involvement in BD patients.
methodsThis cross-sectional observational study was carried out 30 BD patients without known cardiac disease. Patients were subjected to history taking, physical examination, echocardiography and cardiac MRI.
resultsAt least one abnormality on cardiac MRI was observed in 20/30 patients (66.67%). Myocardial oedema was observed in 3 patients (10%) and late gadolinium enhancement in 1 patient (3.3%). Pericardial effusion was found in 3 patients (10.0%), global hypokinesia in 6 patients (20.0%) and intra-cardiac thrombosis in only 1 patient (3.3%). Pulmonary artery was dilated in 4 patients (13.3%). Left ventricular (LV) and right ventricular (RV) end diastolic volume were altered in 4 patients (13.3%) and 7 patients (23.3%) respectively. LV and RV end systolic volume were abnormal in 7 patients (23.3%) and 5 patients (16.7%) respectively. There was aortic valve regurge in 2 patients (6.7%), tricuspid valve regurge in 9 patients (30%), and mitral valve regurge in 9 patients (30%). Dilated left main coronary artery was found in 2 patients (6.7%) and arrhythmogenic right ventricular dysplasia in only one patient 1 patient (3.3%). On logistic regression analysis, BD activity index score was a significant predictor of cardiac abnormalities.
conclusionBD may cause cardiac abnormalities without clinical manifestations and cardiac MRI may represent a tool for early detection of these subtle abnormalities. Higher BD activity index scores are strongly linked to cardiac problems.
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