ArticleCerebral cortex (New York, N.Y. : 1991)2022
Atypical Dynamic Functional Network Connectivity State Engagement during Social-Emotional Processing in Schizophrenia and Autism.
Article in Cerebral cortex (New York, N.Y. : 1991), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Emotion Reactivity and Regulation in Autistic Adults: A Systematic Review Across RDoC Units of Analysis.Psychophysiology · 2025Pooled it
- Alexithymia in Schizophrenia and Psychosis Vulnerability: A Systematic Review and Meta-Analysis.Journal of clinical psychology · 2025Pooled it
- Assessment and correlates of autistic symptoms in Schizophrenia Spectrum Disorders measured with the PANSS Autism Severity Score: A systematic review.Frontiers in psychiatry · 2022Pooled it
- Alexithymia in schizophrenia spectrum disorders and dissociative disorders: two meta-analytic reviews.Schizophrenia (Heidelberg, Germany) · 2026Review
- Transdiagnostic Profiles of BOLD Signal Variability in Autism and Schizophrenia Spectrum Disorders: Associations With Cognition and Functioning.Human brain mapping · 2026Article
- Studying time-resolved functional connectivity via communication theory: on the complementary nature of phase synchronization and sliding window Pearson correlation.bioRxiv : the preprint server for biology · 2025Article
- Brain-wide connectivity changes due to social-emotional regulation during a naturalistic fMRI task.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Altered Patterns of Dynamic Functional Connectivity Underpin Reduced Expressions of Social-Emotional Reciprocity in Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2025Article
- Social functioning and frontal alpha asymmetry in schizophrenia.Journal of psychiatric research · 2025Article
- International perspective on social cognition in schizophrenia: current stage and the next steps.European psychiatry : the journal of the Association of European Psychiatrists · 2025Review
- Aberrant dynamic functional network connectivity in patients with diffuse axonal injury.Scientific reports · 2024Article
- Emotional Contagion and Emotional Mimicry in Individuals with Schizophrenia: A Systematic Review.Journal of clinical medicine · 2024Review
- Task-based functional neural correlates of social cognition across autism and schizophrenia spectrum disorders.Molecular autism · 2024Article
- Identifying Diagnostic Biomarkers for Autism Spectrum Disorder From Higher-order Interactions Using the PED Algorithm.Neuroinformatics · 2024Article
- Spatial-Temporal Characteristics of Brain Activity in Autism Spectrum Disorder Based on Hidden Markov Model and Dynamic Graph Theory: A Resting-State fMRI Study.Brain sciences · 2024Article
- Intrinsic neural timescales in autism spectrum disorder and schizophrenia. A replication and direct comparison study.Schizophrenia (Heidelberg, Germany) · 2023Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
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Abstract
Autism spectrum disorder (ASD) and schizophrenia (SZ) are separate clinical entities but share deficits in social-emotional processing and static neural functional connectivity patterns. We compared patients' dynamic functional network connectivity (dFNC) state engagement with typically developed (TD) individuals during social-emotional processing after initially characterizing such dynamics in TD. Young adults diagnosed with ASD (n = 42), SZ (n = 41), or TD (n = 55) completed three functional MRI runs, viewing social-emotional videos with happy, sad, or neutral content. We examined dFNC of 53 spatially independent networks extracted using independent component analysis and applied k-means clustering to windowed dFNC matrices, identifying four unique whole-brain dFNC states. TD showed differential engagement (fractional time, mean dwell time) in three states as a function of emotion. During Happy videos, patients spent less time than TD in a happy-associated state and instead spent more time in the most weakly connected state. During Sad videos, only ASD spent more time than TD in a sad-associated state. Additionally, only ASD showed a significant relationship between dFNC measures and alexithymia and social-emotional recognition task scores, potentially indicating different neural processing of emotions in ASD and SZ. Our results highlight the importance of examining temporal whole-brain reconfiguration of FNC, indicating engagement in unique emotion-specific dFNC states.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.