Evidence map›Paper›PMID 34875668›Full record

ArticleAmerican journal of nephrology2021

Disparities in Chronic Kidney Disease Progression by Medicare Advantage Enrollees.

Clarissa Jonas Diamantidis, Lindsay Zepel, Virginia Wang, Valerie A Smith, Sarah Hudson Scholle, Loida Tamayo, Matthew L Maciejewski

Open access · bronzeAbstract read
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In one paragraph

Article in American journal of nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Clarissa Jonas DiamantidisDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Lindsay ZepelDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Virginia WangDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Valerie A SmithDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Sarah Hudson ScholleNational Committee for Quality Assurance, Washington, District of Columbia, USA.
Loida TamayoCenters for Medicare & Medicaid Services, Baltimore, Maryland, USA.
Matthew L MaciejewskiDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Duke University · USCenters for Medicare and Medicaid Services · USNational Committee for Quality Assurance · US

Funding

HSRD VA IK6 HX003157
6 · The paper itself

Abstract

introductionThe prevalence of chronic kidney disease (CKD) in Medicare beneficiaries has quadrupled in the past 2 decades, but little is known about risk factors affecting the progression of CKD. This study aims to understand the progression in Medicare Advantage enrollees and whether it differs by provider recognition of CKD, race and ethnicity, or geographic location. In a large cohort of Medicare Advantage (MA) enrollees, we examined whether CKD progression, up to 5 years after study entry, differed by demographic and clinical factors and identified additional risk factors of CKD progression.

methodsIn a cohort of 1,002,388 MA enrollees with CKD stages 1-4 based on 2013-2018 labs, progression was estimated using a mixed-effects model that adjusted for demographics, geographic location, comorbidity, urine albumin-to-creatinine ratio, clinical recognition via diagnosed CKD, and time-fixed effects. Race and ethnicity, geographic location, and clinical recognition of CKD were interacted with time in 3 separate regression models.

resultsMean (median) follow-up was 3.1 (3.0) years. Black and Hispanic MA enrollees had greater kidney function at study entry than other beneficiaries, but their kidney function declined faster. MA enrollees with clinically recognized CKD had estimated glomerular filtration rate levels that were 18.6 units (95% confidence interval [CI]: 18.5-18.7) lower than levels of unrecognized patients, but kidney function declined more slowly in enrollees with clinical recognition. There were no differences in CKD progression by geography. After removal of the race coefficient from the eGFR equation in a sensitivity analysis, kidney function was much lower in all years among Black MA enrollees, but patterns of progression remained the same. DISCUSSION/

conclusionsThese results suggest that patients with clinically recognized CKD and racial and ethnic minorities merit closer surveillance and management to reduce their risk of faster progression.

Indexed as

Disease ProgressionMedicare Part CAdolescentAdultAgedCohort StudiesEthnicityFemaleHealth Status DisparitiesHumansMaleMiddle AgedRacial GroupsRenal Insufficiency, ChronicUnited StatesYoung AdultBeneficiaryChronic kidney diseaseDisparitiesMedicareProgression

Identifiers

PMID34875668
OpenAlexW4200371123

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.