ArticleJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2022
Prevalence of persistent avascular retina in untreated children with a history of retinopathy of prematurity screening.
Article in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The trial behind it
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Incidence and Risk Factors for Persistent Avascular Retina in Patients with a History of Retinopathy of Prematurity in Mexico.Diagnostics (Basel, Switzerland) · 2026Article
- Visualization of the Persistent Avascular Retina with Ultra-Widefield Green Reflectance Imaging.Diagnostics (Basel, Switzerland) · 2025Article
- Persistent avascular retina in retinopathy of prematurity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Review
- A comparation of three different anti-VEGF drugs in development of persistent avascular retina in premature children.Scientific reports · 2024Article
- Extending Peripheral Retinal Vascularization in Retinopathy of Prematurity Through Regulation of VEGF Signaling.American journal of ophthalmology · 2024Article
- Mechanical Ventilation, Retinal Avascularity and Rate of Vascularisation: A Triad of Predictors for Retinopathy of Prematurity Treatment.Journal of personalized medicine · 2024Article
- Macular Thickness Is Associated with Persistent Avascular Retina in Patients with a History of Untreated Retinopathy of Prematurity.Ophthalmology. Retina · 2024Article
- When helping hurts: the unknown effects of common practices in neonatology.Pediatric research · 2023Article
- An Update on Anti-Vascular Endothelial Growth Factor Treatment for Retinopathy of Prematurity.Journal of current ophthalmologyReview
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Persistent avascular retina (PAR) in prematurely born individuals may be a risk factor for late sequelae of retinopathy of prematurity (ROP), including retinal detachment in older childhood and adulthood. Although PAR has been associated with use of vascular endothelial growth factor antagonist therapy for treatment-requiring ROP, the prevalence of this finding in patients without prior ROP treatment is unknown. We performed a cross-sectional study to determine the prevalence of PAR in a cohort of patients 4-8 years of age who were screened for ROP in the neonatal intensive care unit and did not receive treatment. Patients were recruited from an existing population-based cohort and underwent ultra-widefield fluorescein angiography (UWFFA). UWFFA images of 43 eyes of 23 patients were evaluated. Average age at time of evaluation was 6.2 years. PAR was observed in 21 patients (91%). Thirteen eyes (30%) had PAR in zone II; 23 (53%), in zone III. Six eyes (14%) had abnormal vessels without clear PAR. These findings indicate a high prevalence of PAR in patients with a history of ROP screening without treatment.
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Registered trials
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