Evidence map›Paper›PMID 34875255›Full record

ArticleIndian heart journal

Association between serum netrin-1, netrin-4 and risk of the acute coronary syndrome in patients with type 2 diabetes mellitus-A pilot study.

Kumar Inderjeet, Prashant Shankarrao Adole, K V Vinod, Ajith Ananthakrishna Pillai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kumar InderjeetDepartment of Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Prashant Shankarrao AdoleDepartment of Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India. Electronic address: prashant.s@jipmer.edu.in.
K V VinodDepartment of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Ajith Ananthakrishna PillaiDepartment of Cardiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Jawaharlal Institute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was done to assess the diagnostic utility of serum netrin-1 and netrin-4 for recognising the acute coronary syndrome (ACS) in type 2 diabetes mellitus (T2DM) patients. Forty-two T2DM patients with ACS (Cases) and forty-two T2DM patients without ACS (Controls) were compared. Cases had lower serum netrin-1 and netrin-4 levels than controls and were negatively associated with creatinine kinase-total, creatinine kinase-MB, troponin-T and H-FABP. ROC analysis showed that netrin-1 and netrin-4 had good sensitivity and specificity for ACS prediction in T2DM patients. Serum netrin-1 and netrin-4 levels might be considered complementary markers for ACS diagnosis in T2DM patients.

Indexed as

Acute Coronary SyndromeDiabetes Mellitus, Type 2BiomarkersHumansNetrin-1Pilot ProjectsROC CurveBiomarkersNetrin-1NTN1 protein, humanAcute coronary syndromeNetrin-1Netrin-4Type 2 diabetes mellitus

Identifiers

PMID34875255
PMCPMC8891007
OpenAlexW4200533509

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.