Evidence map›Paper›PMID 34875222›Full record

ArticleDevelopmental cell2021

On the location of electrical synapses.

Alberto E Pereda, Adam C Miller

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Defining the electrical synapse.Nature reviews. Neuroscience · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Alberto E PeredaDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: alberto.pereda@einsteinmed.org.
Adam C MillerInstitute of Neuroscience, University of Oregon, Eugene, OR 97403, USA.

Funding

Plasticity of Electrical SynapsesR01DC011099 · NIDCD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Alberto E Pereda · 2010 to 2026
$7.0M
Molecular Mechanisms of Electrical Synapse Formation in VivoR01NS105758 · NINDS · UNIVERSITY OF OREGON · PI Adam C Miller · 2019 to 2026
$3.7M
Transgenic tools for revealing the contributions of electrical synapses to neural circuitsRF1MH120016 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI MILLER, ADAM C, O'BRIEN, JOHN · 2020 to 2020
$3.1M
Generation of transgenic zebrafish to study electrical synaptic transmissionR21NS085772 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI PEREDA, ALBERTO E · 2013 to 2014
$469k
Proteomic analysis of the electrical synapseR21NS117967 · NINDS · UNIVERSITY OF OREGON · PI MILLER, ADAM C · 2020 to 2020
$406k
NIDCD NIH HHS R01 DC011099NINDS NIH HHS R01 NS105758NINDS NIH HHS R21 NS085772
6 · The paper itself

Abstract

Location is of critical functional relevance for synapses, including electrical synapses, which are a form of neuronal communication mediated by cell-cell channels. In this issue of Developmental Cell, Palumbos et al. identify a mechanism that supports the localization and function of electrical synapses with subcellular specificity.

Indexed as

Electrical SynapsesGap JunctionsConnexinsNeuronsSynapsesConnexins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.