Evidence map›Paper›PMID 34875072›Full record

ArticleThe Journal of infectious diseases2022

SARS-CoV-2 Interference of Influenza Virus Replication in Syrian Hamsters.

Peter J Halfmann, Noriko Nakajima, Yuko Sato, Kenta Takahashi, Molly Accola, Shiho Chiba, Shufang Fan, Gabriele Neumann, William Rehrauer, Tadaki Suzuki and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 38 citations in OpenAlex.

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  19. Viral Coinfections.Viruses · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Peter J HalfmannInfluenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-1648-1625
Noriko NakajimaDepartment of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.
Yuko SatoDepartment of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.
Kenta TakahashiDepartment of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.
Molly AccolaUW Health Clinical Laboratories, University of Wisconsin Hospital and Clinics, Madison, Wisconsin, USA.
Shiho ChibaInfluenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Shufang FanInfluenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Gabriele NeumannInfluenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
William RehrauerUW Health Clinical Laboratories, University of Wisconsin Hospital and Clinics, Madison, Wisconsin, USA.
Tadaki SuzukiDepartment of Pathology, National Institute of Infectious Diseases, Tokyo, Japan.
Yoshihiro KawaokaInfluenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
University of Wisconsin–Madison · USNational Institute of Infectious Diseases · JPUW Health University Hospital · US

Funding

Japan Agency for Medical Research and Development JP20fk0108104NIAID NIH HHS HHSN272201400008C
6 · The paper itself

Abstract

In hamsters, SARS-CoV-2 infection at the same time as or before H3N2 influenza virus infection resulted in significantly reduced influenza virus titers in the lungs and nasal turbinates. This interference may be correlated with SARS-CoV-2-induced expression of MX1.

Indexed as

COVID-19Influenza A Virus, H3N2 SubtypeSARS-CoV-2Virus ReplicationAnimalsCoinfectionCricetinaeHumansMesocricetusMyxovirus Resistance ProteinsMyxovirus Resistance ProteinsantiviralCoinfectionInfluenzaMX1SARS-CoV-2

Identifiers

PMID34875072
PMCPMC8689717
OpenAlexW4200576425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.