ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2022
Navigating Black Aging: The Biological Consequences of Stress and Depression.
Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Unexplored avenues: a narrative review of cognition and mood in postmenopausal African women with female genital circumcision/mutilation/cutting.Frontiers in global women's health · 2024Pooled it
- Resilience Mediates the Association Between Discrimination and Psychological Distress Among Rural, Black Women in South Carolina: A Structural Equation Model.Journal of racial and ethnic health disparities · 2026Article
- Adverse policing as a social exposome pathway: Implications for depression, cognition, and dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Molecular markers, mechanisms and metrics of biological aging: a scoping review.Frontiers in aging · 2026Review
- Observational
- Biological Age as a Predictor of Arterial Stiffness in Young and Early Midlife Black and White Women.American journal of hypertension · 2025Article
- Quality of life, religion/spirituality, and dementia risk among Black people in the US.Aging & mental health · 2025Observational
- Aging, Race, and Health Disparities: Recommendations From the Research Centers Collaborative Network.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- The Association Between Grandchild Care and Biological Aging Among Middle-Aged and Older Adults in China.Innovation in aging · 2024Article
- Self-reported experiences of discrimination and incident dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Intersectionality in Alzheimer's Disease: The Role of Female Sex and Black American Race in the Development and Prevalence of Alzheimer's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Review
- Discrimination and Education Quality Moderate the Association of Sleep With Cognitive Function in Older Black Adults: Results From the Einstein Aging Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- More Than Just Race: Redefining the Impact of Sociocultural and Biologic Determinants on Aging and Well-Being of Older Diverse Populations.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesBlack persons in the United States are more likely to suffer from social inequality. Chronic stress caused by social inequality and racial discrimination results in weathering of the body that causes physiological dysregulation and biological age being higher than chronological age (accelerated aging). Depression has been linked to both racial discrimination and accelerated aging and accelerated aging has been demonstrated to be higher in Black than White persons, on average. However, we know little about accelerated aging across the life course in Black Americans.
methodsWe used mixed-effects growth models to measure biological age acceleration, measured with cardiometabolic markers, over a 20-year period in Black participants of the Coronary Artery Risk Development in Young Adults Study who were aged 27-42 years at analytic baseline. We included an interaction between depressive symptoms and time to determine whether risk of depression was associated with a faster rate of biological aging.
resultsWe found that the rate of biological aging increased over a 20-year span and that those at risk for depression had a faster rate of biological aging than those not at risk. We also found that various social factors were associated with biological age acceleration over time. DISCUSSION: Given the known association between perceived racial discrimination and depressive symptoms, we provide a novel instance of the long-term effects of social inequality. Specifically, biological age acceleration, a marker of physiological dysregulation, is associated with time among Black persons and more strongly associated among those with depressive symptoms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.