Evidence map›Paper›PMID 34874892›Full record

ArticleJMIR research protocols2021

Optimizing a Just-in-Time Adaptive Intervention to Improve Dietary Adherence in Behavioral Obesity Treatment: Protocol for a Microrandomized Trial.

Stephanie P Goldstein, Fengqing Zhang, Predrag Klasnja, Adam Hoover, Rena R Wing, John Graham Thomas

3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in JMIR research protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04784585 naactive not recruitingnot on this map

Optimizing Just-in-Time Adaptive Intervention to Improve Dietary Adherence in Behavioral Obesity Treatment: A Micro-randomized Trial

TypeinterventionalSponsorThe Miriam HospitalRan2021 to 2026Enrolled204ConditionsObesityArmsJITAI Enhanced Education Intervention Option, JITAI Self-Efficacy Intervention Option, JITAI Motivation Intervention Option, JITAI Self-Regulation Intervention Option, JITAI Generic Risk Alert Intervention Option (Active Comparator)
NCT06783907 nacompletednot on this mapstarted 2023, after this paper: background citation

Technological-based Personalized Care Intervention for Supporting Older People With Diabetes Mellitus

TypeinterventionalSponsorHong Kong Metropolitan UniversityRan2023 to 2025Enrolled60ConditionsDiabetes MellitusArmsNon-invasive blood glucose monitoring, Traditional blood glucose monitoring
NCT07746492 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Digital Real-Time Support for Stress-Induced Smoking and Unhealthy Eating Among Gender and Sexual Minorities in Dhaka

TypeinterventionalSponsorInternational Centre for Diarrhoeal Disease Research, BangladeshRan2026 to 2027Enrolled115ConditionsTobacco Use, Electronic Cigarette Use, Emotional Eating, Stress, PsychologicalArmsJust-in-Time Adaptive Support Message
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Stephanie P GoldsteinWeight Control and Diabetes Research Center, The Miriam Hospital, Providence, RI, United States.ORCID https://orcid.org/0000-0002-9656-1675
Fengqing ZhangDepartment of Psychology, Drexel University, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0003-2736-2303
Predrag KlasnjaSchool of Information, University of Michigan, Ann Arbor, MI, United States.ORCID https://orcid.org/0000-0002-4570-703X
Adam HooverHolcombe Department of Electrical and Computer Engineering, Clemson University, Clemson, SC, United States.ORCID https://orcid.org/0000-0003-2965-6524
Rena R WingWeight Control and Diabetes Research Center, The Miriam Hospital, Providence, RI, United States.ORCID https://orcid.org/0000-0002-0918-8252
John Graham ThomasWeight Control and Diabetes Research Center, The Miriam Hospital, Providence, RI, United States.ORCID https://orcid.org/0000-0001-7549-2431
Brown University · USClemson University · USDrexel University · USUniversity of Michigan · US

Funding

Optimizing Just-in-Time Adaptive Intervention to Improve Dietary Adherence in Behavioral Obesity Treatment: A Micro-randomized TrialR01HL153543 · NHLBI · MIRIAM HOSPITAL · PI GOLDSTEIN, STEPHANIE PAIGE · 2020 to 2023
$2.6M
NHLBI NIH HHS R01 HL153543
6 · The paper itself

Abstract

backgroundBehavioral obesity treatment (BOT) is a gold standard approach to weight loss and reduces the risk of cardiovascular disease. However, frequent lapses from the recommended diet stymie weight loss and prevent individuals from actualizing the health benefits of BOT. There is a need for innovative treatment solutions to improve adherence to the prescribed diet in BOT.

objectiveThe aim of this study is to optimize a smartphone-based just-in-time adaptive intervention (JITAI) that uses daily surveys to assess triggers for dietary lapses and deliver interventions when the risk of lapse is high. A microrandomized trial design will evaluate the efficacy of any interventions (ie, theory-driven or a generic alert to risk) on the proximal outcome of lapses during BOT, compare the effects of theory-driven interventions with generic risk alerts on the proximal outcome of lapse, and examine contextual moderators of interventions.

methodsAdults with overweight or obesity and cardiovascular disease risk (n=159) will participate in a 6-month web-based BOT while using the JITAI to prevent dietary lapses. Each time the JITAI detects elevated lapse risk, the participant will be randomized to no intervention, a generic risk alert, or 1 of 4 theory-driven interventions (ie, enhanced education, building self-efficacy, fostering motivation, and improving self-regulation). The primary outcome will be the occurrence of lapse in the 2.5 hours following randomization. Contextual moderators of intervention efficacy will also be explored (eg, location and time of day). The data will inform an optimized JITAI that selects the theory-driven approach most likely to prevent lapses in a given moment.

resultsThe recruitment for the microrandomized trial began on April 19, 2021, and is ongoing.

conclusionsThis study will optimize a JITAI for dietary lapses so that it empirically tailors the provision of evidence-based intervention to the individual and context. The finalized JITAI will be evaluated for efficacy in a future randomized controlled trial of distal health outcomes (eg, weight loss).

trial registrationClinicalTrials.gov NCT04784585; http://clinicaltrials.gov/ct2/show/NCT04784585. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/33568.

Indexed as

dietary adherencejust-in-time adaptive interventionmicrorandomized trialmobile phoneobesityweight loss

Identifiers

PMID34874892
PMCPMC8691411
OpenAlexW4200299471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.