Evidence map›Paper›PMID 34874614›Full record

ArticleTransboundary and emerging diseases2022

A novel enterovirus in lambs with poliomyelitis and brain stem encephalitis.

Herbert Weissenböck, Arnt Ebinger, Anna Maria Gager, Denise Thaller, Dirk Höper, Katharina Lichtmannsperger, Christiane Weissenbacher-Lang, Julia Matt, Martin Beer

Open access · hybridAbstract read
In one paragraph

Article in Transboundary and emerging diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Herbert WeissenböckInstitute of Pathology, Department of Pathobiology, Vienna, Austria.ORCID https://orcid.org/0000-0001-8197-6379
Arnt EbingerFriedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Diagnostic Virology, Greifswald, Germany.
Anna Maria GagerInstitute of Pathology, Department of Pathobiology, Vienna, Austria.ORCID https://orcid.org/0000-0003-3446-0948
Denise ThallerInstitute of Pathology, Department of Pathobiology, Vienna, Austria.
Dirk HöperFriedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Diagnostic Virology, Greifswald, Germany.ORCID https://orcid.org/0000-0001-8408-2274
Katharina LichtmannspergerUniversity Clinic for Ruminants, Vienna, Austria.
Christiane Weissenbacher-LangInstitute of Pathology, Department of Pathobiology, Vienna, Austria.
Julia MattInstitute of Pathology, Department of Pathobiology, Vienna, Austria.
Martin BeerFriedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Diagnostic Virology, Greifswald, Germany.
University of Veterinary Medicine Vienna · ATFriedrich-Loeffler-Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An Austrian organic dairy sheep farm experienced cases of recumbency and sudden deaths in 3- to 4-week-old lambs. Two animals were subjected to thorough clinical and pathological investigations. Pathohistological analysis identified severe nonsuppurative myelitis and mild nonsuppurative encephalitis. A reverse-transcription quantitative PCR (RT-qPCR) assay for the recently discovered ovine picornavirus causing comparable lesions scored negative. By next-generation sequencing-based metagenomics, a nearly complete genome of a novel enterovirus could be detected and assembled. In situ hybridization using a specifically designed probe revealed robust signals in affected motoneurons of the spinal cord suggesting a causative role of the novel virus.

Indexed as

EncephalitisEnterovirusEnterovirus InfectionsPoliomyelitisAnimalsBrain StemSheepSheep, Domesticencephalomyelitisenterovirusin situ hybridizationlambnext-generation sequencing

Identifiers

PMID34874614
PMCPMC9305294
OpenAlexW4200155814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.