Evidence map›Paper›PMID 34874494›Full record

ArticleJapanese journal of radiology2022

Assessment of esophagogastric junction morphology by dynamic real-time MRI: comparison of imaging features to high-resolution manometry.

Lorenz Biggemann, Johannes Uhlig, Nina Gliem, Omar Al-Bourini, Edris Wedi, Volker Ellenrieder, Michael Ghadimi, Martin Uecker, Jens Frahm, Joachim Lotz and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Japanese journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Lorenz BiggemannDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany. lorenz.biggemann@med.uni-goettingen.de.
Johannes UhligDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.
Nina GliemDepartment of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen, Germany.
Omar Al-BouriniDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.
Edris WediDepartment of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen, Germany.
Volker EllenriederDepartment of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen, Germany.
Michael GhadimiDepartment of General, Visceral, and Paediatric Surgery, University Medical Center, Göttingen, Germany.
Martin UeckerDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.
Jens FrahmBiomedical NMR, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
Joachim LotzDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.
Ali Seif Amir HosseiniDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.
Ulrike StreitDepartment of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.
Universitätsmedizin Göttingen · DEMax Planck Institute for Biophysical Chemistry · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the esophagogastric junction (EGJ) on real-time MRI and compare imaging parameters to EGJ morphology on high-resolution manometry (HRM).

methodsA total of 105 of 117 eligible patients who underwent real-time MRI and high-resolution manometry for GERD-like symptoms between 2015 and 2018 at a single center were retrospectively evaluated (male n = 57; female n = 48; mean age 52.5 ± 15.4 years). Real-time MRI was performed at a median investigation time of 15 min (1 frame/40 ms). On HRM, EGJ morphology was assessed according to the Chicago classification of esophageal motility disorders. Real-time MRI was performed at 3 T using highly undersampled radial fast low-angle shot acquisitions with NLINV image reconstruction. A 10 mL pineapple juice bolus served as oral contrast agent at supine position. Real-time MRI films of the EGJ were acquired during swallowing events and during Valsalva maneuver. Anatomic and functional MRI parameters were compared to EGJ morphology on HRM.

resultsOn HRM, n = 42 patients presented with EGJ type I (40.0%), n = 33 with EGJ type II (31.4%), and n = 30 with EGJ type III (28.6%). On real-time MRI, hiatal hernia was more common in patients with EGJ type III (66.7%) than in patients with EGJ type I (26.2%) and EGJ type II (30.3%; p < 0.001). Sliding hiatal hernia was more frequent in patients with EGJ type II (33.3%) than in patients with EGJ type III (16.7%) and EGJ type I (7.1%; p = 0.017). The mean esophagus-fundus angle of patients was 85 ± 31° at rest and increased to 101 ± 36° during Valsalva maneuver.

conclusionReal-time MRI is a non-invasive imaging method for assessment of the esophagogastric junction. Real-time MRI can visualize dynamic changes of the EGJ during swallowing events.

Indexed as

Gastroesophageal RefluxAdultAgedEsophagogastric JunctionFemaleHumansMagnetic Resonance ImagingMaleManometryMiddle AgedRetrospective StudiesEGJEsophagogastric junctionHigh-resolution manometryHRMReal-time MRI

Identifiers

PMID34874494
PMCPMC8977262
OpenAlexW4200268109

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.