Evidence map›Paper›PMID 34874214›Full record

ArticleBrain injury2021

Subjective executive dysfunction in patients with primary brain tumors and their informants: relationships with neurocognitive, psychological, and daily functioning.

Sarah Ellen Braun, Autumn Lanoye, Farah J Aslanzadeh, Ashlee R Loughan

Abstract read
In one paragraph

Article in Brain injury, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Self- and informant-reported cognitive concerns associated with primary brain tumour: systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah Ellen BraunDepartment of Neurology, Virginia Commonwealth University, Richmond, Virginia, USA.
Autumn LanoyeMassey Cancer Center, Richmond, Virginia, USA.ORCID 0000-0003-3705-0880
Farah J AslanzadehDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.
Ashlee R LoughanDepartment of Neurology, Virginia Commonwealth University, Richmond, Virginia, USA.

Funding

Institutional Career Development CoreKL2TR002648 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI NANASINKAM, SERGE PATRICK, SANYAL, ARUN J · 2018 to 2022
$3.7M
CTSA K12 Program at Virginia Commonwealth UniversityK12TR004364 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI SERGE PATRICK NANASINKAM, Gretchen N Neigh · 2023 to 2026
$3.0M
NCATS NIH HHS K12 TR004364NCATS NIH HHS KL2 TR002648
6 · The paper itself

Abstract

objectiveWe assessed agreement between patient- and informant-report on the Behavior Rating Inventory of Executive Function - Adult (BRIEF-A) in patients with primary brain tumors (PBT) and differences on BRIEF-A in neurocognitive (intact v. impaired), psychological (asymptomatic v. distressed), and functional (independent v. dependent) categories using both patient- and informant-report.

methodPBT patients (n = 102) completed neuropsychological evaluations including the BRIEF-A, clinical interview, neurocognitive tests, and mood questionnaires. Correlations between the BRIEF-A and Informant (n = 39) were conducted. Differences in patient and informant BRIEF-A indices were investigated across five classifications: neurocognitive functioning, psychological functioning, medication management, appointment management, and finance management.

resultsPatient and informant BRIEF were correlated. There was no difference on BRIEF-A or Informant indices for intact v. impaired neurocognitive status. Higher BRIEF-A and Informant indices were observed among psychologically distressed v. asymptomatic patients. Results showed higher BRIEF indices among those requiring assistance with medication, appointments, and finances.

conclusionsPatients and informants agreed in their reports of executive function (EF). These reports, while not different in neurocognitive classification, were different in psychological functioning and in those needing assistance with instrumental activities of daily living (IADL). Patient- and informant-reported EF may provide important data regarding psychological and IADL functioning in this population.

Indexed as

Brain NeoplasmsCognitive DysfunctionActivities of Daily LivingAdultExecutive FunctionHumansNeuropsychological TestsBRIEF-adultBRIEF-informantexecutive functioninginstrumental activities of daily livingneuro-oncologyprimary brain tumor

Identifiers

PMID34874214
PMCPMC8875322

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.