Evidence map›Paper›PMID 34873557›Full record

ArticleCureus2021

Comparison of Cardiac Autonomic Function in Type 2 Spinocerebellar Ataxia With Normal Control Using Heart Rate Variability as a Tool: A Cross-Sectional Study in Eastern India.

Laxman K Senapati, Sudipta Patnaik, Priyadarsini Samanta, Sambit P Kar, Santosh Dash, Jayanti Mishra

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Laxman K SenapatiDepartment of Anesthesia, Kalinga Institute of Medical Sciences, Kalinga Institute of Industrial Technology (KIIT, deemed to be University), Bhubaneswar, IND.
Sudipta PatnaikDepartment of Physiology, Sriram Chandra Bhanja Medical College, Utkal University, Bhubaneswar, IND.
Priyadarsini SamantaDepartment of Physiology, Kalinga Institute of Medical Sciences, Kalinga Institute of Industrial Technology (KIIT, deemed to be University), Bhubaneswar, IND.
Sambit P KarResearch, School of Electronics Engineering, Kalinga Institute of Industrial Technology (KIIT, deemed to be University), Bhubaneswar, IND.
Santosh DashDepartment of Neurology, Kalinga Institute of Medical Sciences, Kalinga Institute of Industrial Technology (KIIT, deemed to be University), Bhubaneswar, IND.
Jayanti MishraDepartment of Physiology, Kalinga Institute of Medical Sciences, Kalinga Institute of Industrial Technology (KIIT, deemed to be University), Bhubaneswar, IND.
Siksha O Anusandhan University · INUtkal University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpinocerebellar ataxia (SCA) is a disease that refers to a category of inherited ataxias that are characterized by degenerative alterations in the cerebellum, pons, and spinocerebellar tracts. There are several different varieties of SCA and they are classified based on the mutant (altered) gene that causes the disease.

objectiveTo analyze the cardiovascular autonomic regulation in patients with type-2 spinocerebellar ataxia (SCA-2) from the heart rate variability (HRV) of 20 minutes resting electrocardiogram (ECG) and compare with the age and gender-matched controls. MATERIALS AND

methodsHRV of 27 type-2 spinocerebellar ataxia patients was calculated offline from the resting ECG recording and compared with 23 age and gender-matched controls. The HRV was analyzed by HRV software module MLS 310. The frequency and time domain parameters were computed and compared.

resultType-2 spinocerebellar ataxia patients have significantly low HRV and parasympathetic activity at rest compared to normal control. The total power in SCA-2 is 13491.63 ± 7660.77 ms

conclusionThere is decreased parasympathetic tone and low HRV in SCA-2 as compared to normal controls.

Indexed as

cardiac autonomic functionheart rate variabilityparasympathetic tonespinocerebellar ataxiasympathetic tone

Identifiers

PMID34873557
PMCPMC8632594
OpenAlexW3216201412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.